Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
3.2.2.-
Hydrolases;
Glycosylases;
Hydrolysing N-glycosyl compounds;
3.5.1.-
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides;
PDB | Resolution (Å) | PDB name |
---|---|---|
4IQY | 1.55 | Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2 |
6Y4Y | 1.75 | The crystal structure of human MACROD2 in space group P41212 |
6Y4Z | 1.9 | The crystal structure of human MACROD2 in space group P43212 |
6Y73 | 1.7 | The crystal structure of human MACROD2 in space group P43 |
GO ontology | GO term | GO description |
---|---|---|
Biological Process | GO:0006974 | DNA damage response |
Biological Process | GO:0007420 | brain development |
Biological Process | GO:0140291 | peptidyl-glutamate ADP-deribosylation |
Biological Process | GO:0051725 | protein de-ADP-ribosylation |
Biological Process | GO:0042278 | purine nucleoside metabolic process |
Biological Process | GO:0009617 | response to bacterium |
Molecular Function | GO:0140293 | ADP-ribosylglutamate hydrolase activity |
Molecular Function | GO:0019213 | deacetylase activity |
Molecular Function | GO:0016798 | hydrolase activity, acting on glycosyl bonds |
Cellular Component | GO:0005730 | nucleolus |
Cellular Component | GO:0005654 | nucleoplasm |
Cellular Component | GO:0005634 | nucleus |
Location | ECO term | Pubmed |
---|---|---|
Nucleus | ECO:0000269 | PubMed:23474712 |