Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
6.2.1.15
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases;
arachidonate—CoA ligase
6.2.1.2
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases;
medium-chain acyl-CoA ligase
6.2.1.3
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases;
long-chain-fatty-acid—CoA ligase
| PDB | Resolution (Å) | PDB name |
|---|
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0006631 | fatty acid metabolic process |
| Biological Process | GO:0044539 | long-chain fatty acid import into cell |
| Biological Process | GO:0001676 | long-chain fatty acid metabolic process |
| Biological Process | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process |
| Biological Process | GO:0035336 | long-chain fatty-acyl-CoA metabolic process |
| Biological Process | GO:0030182 | neuron differentiation |
| Biological Process | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport |
| Biological Process | GO:2001247 | positive regulation of phosphatidylcholine biosynthetic process |
| Biological Process | GO:0051047 | positive regulation of secretion |
| Biological Process | GO:0034379 | very-low-density lipoprotein particle assembly |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0047676 | arachidonate-CoA ligase activity |
| Molecular Function | GO:0004467 | long-chain fatty acid-CoA ligase activity |
| Molecular Function | GO:0031956 | medium-chain fatty acid-CoA ligase activity |
| Molecular Function | GO:0090433 | palmitoyl-CoA ligase activity |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0005811 | lipid droplet |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005778 | peroxisomal membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-434313 | Intracellular metabolism of fatty acids regulates insulin secretion | Leaf | R-HSA-1430728 | Metabolism |
| R-HSA-75876 | Synthesis of very long-chain fatty acyl-CoAs | Leaf | R-HSA-1430728 | Metabolism |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Endoplasmic reticulum membrane | ECO:0000250 | |
| Microsome membrane | ECO:0000250 | |
| Mitochondrion outer membrane | ECO:0000250 | |
| Peroxisome membrane | ECO:0000250 |