| 1I10 |
2.3 |
HUMAN MUSCLE L-LACTATE DEHYDROGENASE M CHAIN, TERNARY COMPLEX WITH NADH AND OXAMATE |
| 4AJP |
2.38 |
Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid |
| 4JNK |
1.896 |
Lactate Dehydrogenase A in complex with inhibitor compound 22 |
| 4L4R |
2.1 |
Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme |
| 4L4S |
2.9 |
Structural characterisation of the NADH binary complex of human lactate dehydrogenase M isozyme |
| 4M49 |
2.052 |
Lactate Dehydrogenase A in complex with a substituted pyrazine inhibitor compound 18 |
| 4OJN |
2.4 |
Crystal structure of human muscle L-lactate dehydrogenase |
| 4OKN |
2.1 |
Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate |
| 4QO7 |
2.14 |
Lactate Dehydrogenase A in complex with substituted 3-Hydroxy-2-mercaptocyclohex-2-enone compound 7 |
| 4QO8 |
2.001 |
Lactate Dehydrogenase A in complex with substituted 3-Hydroxy-2-mercaptocyclohex-2-enone compound 104 |
| 4QSM |
3.0 |
Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid |
| 4QT0 |
3.2 |
Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 1, 3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL)QUINOLIN-4-YL]AMINO}BENZOIC ACID |
| 4R68 |
2.112 |
Lactate Dehydrogenase in complex with inhibitor compound 31 |
| 4R69 |
3.19 |
Lactate Dehydrogenase in complex with inhibitor compound 13 |
| 4RLS |
1.91 |
Lactate Dehydrogenase in complex with inhibitor compound 47 |
| 4ZVV |
2.2 |
Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140 |
| 5IXS |
2.05 |
Lactate Dehydrogenase in complex with hydroxylactam inhibitor compound 9: (6R)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(3-hydroxyphenyl)-6-(thiophen-3-yl)-5,6-dihydropyridin-2(1H)-one |
| 5IXY |
3.0 |
Lactate Dehydrogenase in complex with hydroxylactam inhibitor compound 31: (2~{S})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one |
| 5W8H |
1.8 |
Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 11 |
| 5W8I |
1.95 |
Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 23 and Zinc |
| 5W8J |
1.55 |
Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 |
| 5W8K |
1.6 |
Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 29 and NADH |
| 5W8L |
1.95 |
Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 59 and NADH |
| 5ZJD |
2.394 |
Lactate dehydrogenase with NADH and MLA |
| 5ZJE |
2.929 |
LDHA-mla |
| 5ZJF |
2.602 |
LDHA-MA |
| 6BAD |
2.1 |
Lactate Dehydrogenase in complex with inhibitor (R)-3-((2-chlorophenyl)thio)-6-(3-((4-fluorophenyl)amino)phenyl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one |
| 6BAG |
2.4 |
Lactate Dehydrogenase in complex with inhibitor (R)-5-((2-chlorophenyl)thio)-6'-((4-fluorophenyl)amino)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1H)-one |
| 6BAX |
2.05 |
Lactate Dehydrogenase in complex with inhibitor 6-(3-aminophenyl)-3-((2-chlorophenyl)thio)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one |
| 6BAZ |
2.7 |
Lactate Dehydrogenase in complex with inhibitor (S)-5-((2-chlorophenyl)thio)-6'-((4-fluorophenyl)amino)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1H)-one |
| 6BB0 |
1.95 |
Lactate Dehydrogenase in complex with inhibitor (R)-3-((2-chlorophenyl)thio)-6-(3-((4-fluorophenyl)amino)phenyl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one |
| 6BB1 |
2.3 |
Lactate Dehydrogenase in complex with inhibitor (R)-5-((2-chlorophenyl)thio)-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1H)-one |
| 6BB2 |
2.47 |
Lactate Dehydrogenase in complex with inhibitor (S)-5-((2-chlorophenyl)thio)-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1H)-one |
| 6BB3 |
2.4 |
Lactate Dehydrogenase in complex with inhibitor 3-((2-chlorophenyl)thio)-6-(6-((4-fluorophenyl)amino)pyridin-2-yl)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one |
| 6MV8 |
1.95 |
LDHA structure in complex with inhibitor 14 |
| 6MVA |
2.02 |
LDHA structure in complex with inhibitor 14 |
| 6Q0D |
2.05 |
CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00384414-01 AT 2.05 A RESOLUTION |
| 6Q13 |
2.0 |
CRYSTAL STRUCTURE OF LDHA IN COMPLEX WITH COMPOUND NCGC00420737-09 AT 2.00 A RESOLUTION |
| 6SBU |
2.91 |
X-ray Structure of Human LDHA with an Allosteric Inhibitor (Compound 3) |
| 6SBV |
2.6 |
X-ray Structure of Human LDH-A with an Allosteric Inhibitor (Compound 7) |
| 6ZZR |
2.65 |
The Crystal Structure of human LDHA from Biortus |
| 7M2N |
2.5 |
Crystal structure of Human Lactate Dehydrogenase A with Inhibitor Compound 15 |
