Protein family
The protein has not catalytic activity
Protein sequence
Protein function
Catalytic activity
PDB | Resolution (Å) | PDB name |
---|---|---|
4V6W | 6.0 | Structure of the D. melanogaster 80S ribosome |
4V6X | 5.0 | Structure of the human 80S ribosome |
5AJ0 | 3.5 | Cryo electron microscopy of actively translating human polysomes (POST state). |
6OLG | 3.4 | Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) |
6ZM7 | 2.7 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex |
6ZME | 3.0 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex |
6ZMI | 2.6 | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex |
6ZMO | 3.1 | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex |
GO ontology | GO term | GO description |
---|---|---|
Biological Process | GO:0002181 | cytoplasmic translation |
Biological Process | GO:0000027 | ribosomal large subunit assembly |
Biological Process | GO:0006412 | translation |
Molecular Function | GO:0003723 | RNA binding |
Molecular Function | GO:0070180 | large ribosomal subunit rRNA binding |
Molecular Function | GO:0003735 | structural constituent of ribosome |
Cellular Component | GO:0005737 | cytoplasm |
Cellular Component | GO:0036464 | cytoplasmic ribonucleoprotein granule |
Cellular Component | GO:0005829 | cytosol |
Cellular Component | GO:0022625 | cytosolic large ribosomal subunit |
Cellular Component | GO:0022626 | cytosolic ribosome |
Cellular Component | GO:0005783 | endoplasmic reticulum |
Cellular Component | GO:0070062 | extracellular exosome |
Cellular Component | GO:0005925 | focal adhesion |
Cellular Component | GO:0016020 | membrane |
Cellular Component | GO:0005634 | nucleus |
Cellular Component | GO:0098794 | postsynapse |
Cellular Component | GO:0014069 | postsynaptic density |
Cellular Component | GO:1990904 | ribonucleoprotein complex |
InterPro | InterPro name |
---|---|
IPR001790 | Ribosomal protein L10P |
IPR030670 | 60S acidic ribosomal protein P0 |
IPR040637 | 60S ribosomal protein L10P, insertion domain |
IPR043141 | Ribosomal protein L10-like domain superfamily |
IPR043164 | 50S ribosomal protein L10, insertion domain superfamily |
Pfam | Pfam name |
---|---|
PF00428 | 60s Acidic ribosomal protein |
PF00466 | Ribosomal protein L10 |
PF17777 | Insertion domain in 60S ribosomal protein L10P |
Reactome | Reactome Name | Node type | Reactome Root | Reactome Root Name |
---|---|---|---|---|
R-HSA-156827 | L13a-mediated translational silencing of Ceruloplasmin expression | Leaf | R-HSA-392499 | Metabolism of proteins |
R-HSA-156902 | Peptide chain elongation | Leaf | R-HSA-392499 | Metabolism of proteins |
R-HSA-1799339 | SRP-dependent cotranslational protein targeting to membrane | Leaf | R-HSA-392499 | Metabolism of proteins |
R-HSA-192823 | Viral mRNA Translation | Leaf | R-HSA-1643685 | Disease |
R-HSA-2408557 | Selenocysteine synthesis | Leaf | R-HSA-1430728 | Metabolism |
R-HSA-6791226 | Major pathway of rRNA processing in the nucleolus and cytosol | Leaf | R-HSA-8953854 | Metabolism of RNA |
R-HSA-72689 | Formation of a pool of free 40S subunits | Leaf | R-HSA-392499 | Metabolism of proteins |
R-HSA-72706 | GTP hydrolysis and joining of the 60S ribosomal subunit | Leaf | R-HSA-392499 | Metabolism of proteins |
R-HSA-72764 | Eukaryotic Translation Termination | Leaf | R-HSA-392499 | Metabolism of proteins |
R-HSA-8950505 | Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation | Leaf | R-HSA-168256 | Immune System |
R-HSA-9010553 | Regulation of expression of SLITs and ROBOs | Leaf | R-HSA-1266738 | Developmental Biology |
R-HSA-9633012 | Response of EIF2AK4 (GCN2) to amino acid deficiency | Leaf | R-HSA-8953897 | Cellular responses to stimuli |
R-HSA-975956 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | Leaf | R-HSA-8953854 | Metabolism of RNA |
R-HSA-975957 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | Leaf | R-HSA-8953854 | Metabolism of RNA |
Location | ECO term | Pubmed |
---|---|---|
Cytoplasm | ECO:0000269 | PubMed:19188445 |
Nucleus | ECO:0000269 | PubMed:19188445 |