Structure
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 1A02 | 2.7 | STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA |
| 1FOS | 3.05 | TWO HUMAN C-FOS:C-JUN:DNA COMPLEXES |
| 1JNM | 2.2 | Crystal Structure of the Jun/CRE Complex |
| 1JUN | NMR STUDY OF C-JUN HOMODIMER | |
| 1S9K | 3.1 | Crystal Structure of Human NFAT1 and Fos-Jun on the IL-2 ARRE1 Site |
| 1T2K | 3.0 | Structure Of The DNA Binding Domains Of IRF3, ATF-2 and Jun Bound To DNA |
| 5FV8 | 1.99 | Structure of cJun-FosW coiled coil complex. |
| 5T01 | 1.89 | Human c-Jun DNA binding domain homodimer in complex with methylated DNA |
| 6Y3V | 1.499 | 14-3-3 Sigma in complex with phosphorylated c-Jun peptide |
Showing 1 to 9 of 9 entries
GO term
GO ontology
| GO term | GO description |
|---|---|---|
| Biological Process | GO:0060395 | SMAD protein signal transduction |
| Biological Process | GO:0001525 | angiogenesis |
| Biological Process | GO:0006915 | apoptotic process |
| Biological Process | GO:0031103 | axon regeneration |
| Biological Process | GO:0008283 | cell population proliferation |
| Biological Process | GO:0072740 | cellular response to anisomycin |
| Biological Process | GO:0071276 | cellular response to cadmium ion |
| Biological Process | GO:0071277 | cellular response to calcium ion |
| Biological Process | GO:0034614 | cellular response to reactive oxygen species |
| Biological Process | GO:0061029 | eyelid development in camera-type eye |
Showing 1 to 10 of 70 entries
InterPro / Pfam
Reactome
| Reactome
| Reactome Name | Node type
| Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-1912408 | Pre-NOTCH Transcription and Translation | Leaf | R-HSA-162582 | Signal Transduction |
| R-HSA-2559580 | Oxidative Stress Induced Senescence | Leaf | R-HSA-8953897 | Cellular responses to stimuli |
| R-HSA-2559582 | Senescence-Associated Secretory Phenotype (SASP) | Leaf | R-HSA-8953897 | Cellular responses to stimuli |
| R-HSA-2871796 | FCERI mediated MAPK activation | Leaf | R-HSA-168256 | Immune System |
| R-HSA-450341 | Activation of the AP-1 family of transcription factors | Leaf | R-HSA-168256 | Immune System |
| R-HSA-5617472 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | Leaf | R-HSA-1266738 | Developmental Biology |
| R-HSA-5687128 | MAPK6/MAPK4 signaling | Leaf | R-HSA-162582 | Signal Transduction |
| R-HSA-6796648 | TP53 Regulates Transcription of DNA Repair Genes | Leaf | R-HSA-74160 | Gene expression (Transcription) |
| R-HSA-8862803 | Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | Leaf | R-HSA-1643685 | Disease |
| R-HSA-8943724 | Regulation of PTEN gene transcription | Leaf | R-HSA-162582 | Signal Transduction |
Showing 1 to 10 of 12 entries
Interactor | Variant | Drug
Tissue and cell type
| Tissue
| Cell type
| Expression level | Reliability |
|---|---|---|---|
| adrenal gland | glandular cells | Low | Enhanced |
| appendix | glandular cells | Medium | Enhanced |
| breast | adipocytes | Low | Enhanced |
| breast | glandular cells | Medium | Enhanced |
| cerebellum | granular cells - nucleus | High | Enhanced |
| cerebellum | white matter cells - nucleus | Medium | Enhanced |
| cerebral cortex | neuronal cells | Low | Enhanced |
| cervix | squamous epithelial cells | Medium | Enhanced |
| colon | endothelial cells | Low | Enhanced |
| colon | glandular cells | Medium | Enhanced |
Showing 1 to 10 of 47 entries