| 1GW6 |
2.2 |
STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT |
| 1H19 |
2.1 |
STRUCTURE OF [E271Q]LEUKOTRIENE A4 HYDROLASE |
| 1HS6 |
1.95 |
STRUCTURE OF LEUKOTRIENE A4 HYDROLASE COMPLEXED WITH BESTATIN. |
| 1SQM |
2.3 |
STRUCTURE OF [R563A] LEUKOTRIENE A4 HYDROLASE |
| 2R59 |
1.89 |
Leukotriene A4 hydrolase complexed with inhibitor RB3041 |
| 2VJ8 |
1.8 |
Complex of human leukotriene A4 hydrolase with a hydroxamic acid inhibitor |
| 3B7R |
1.811 |
Leukotriene A4 Hydrolase Complexed with Inhibitor RB3040 |
| 3B7S |
1.465 |
[E296Q]LTA4H in complex with RSR substrate |
| 3B7T |
2.3 |
[E296Q]LTA4H in complex with Arg-Ala-Arg substrate |
| 3B7U |
1.9 |
Leukotriene A4 Hydrolase Complexed with KELatorphan |
| 3CHO |
1.8 |
Crystal structure of leukotriene a4 hydrolase in complex with 2-amino-N-[4-(phenylmethoxy)phenyl]-acetamide |
| 3CHP |
2.1 |
Crystal structure of leukotriene a4 hydrolase in complex with (3S)-3-amino-4-oxo-4-[(4-phenylmethoxyphenyl)amino]butanoic acid |
| 3CHQ |
2.09 |
Crystal structure of leukotriene a4 hydrolase in complex with N5-[4-(phenylmethoxy)phenyl]-L-glutamine |
| 3CHR |
2.2 |
Crystal structure of leukotriene A4 hydrolase in complex with 4-amino-N-[4-(phenylmethoxy)phenyl]-butanamide |
| 3CHS |
2.55 |
Crystal structure of leukotriene A4 hydrolase in complex with (2S)-2-amino-5-[[4-[(2S)-2-hydroxy-2-phenyl-ethoxy]phenyl]amino]-5-oxo-pentanoic acid |
| 3FH5 |
1.63 |
Leukotriene A4 Hydrolase complexed with inhibitor (2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine. |
| 3FH7 |
2.05 |
Leukotriene A4 Hydrolase complexed with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate. |
| 3FH8 |
1.67 |
Leukotriene A4 Hydrolase complexed with inhibitor 1-[2-(4-benzylphenoxy)ethyl]pyrrolidine. |
| 3FHE |
2.16 |
Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine. |
| 3FTS |
2.33 |
Leukotriene A4 hydrolase in complex with resveratrol |
| 3FTU |
1.9 |
Leukotriene A4 hydrolase in complex with dihydroresveratrol |
| 3FTV |
1.7 |
Leukotriene A4 hydrolase in complex with fragment N-(pyridin-3-ylmethyl)aniline |
| 3FTW |
1.85 |
Leukotriene A4 hydrolase in complex with fragments N-(pyridin-3-ylmethyl)aniline and acetate |
| 3FTX |
1.96 |
Leukotriene A4 hydrolase in complex with dihydroresveratrol and bestatin |
| 3FTY |
2.15 |
Leukotriene A4 hydrolase in complex with fragment 3-(benzyloxy)pyridin-2-amine |
| 3FTZ |
2.0 |
Leukotriene A4 hydrolase in complex with fragment 2-(pyridin-3-ylmethoxy)aniline |
| 3FU0 |
1.8 |
Leukotriene A4 hydrolase in complex with fragment 4-(4-fluorobenzoyl)pyridine |
| 3FU3 |
2.0 |
Leukotriene A4 hydrolase in complex with fragment 4-(2-amino-1,3-thiazol-4-yl)phenol |
| 3FU5 |
2.3 |
Leukotriene A4 hydrolase in complex with (5-thiophen-2-ylthiophen-2-yl)methylamine |
| 3FU6 |
2.05 |
Leukotriene A4 hydrolase in complex with fragment (4-thiophen-2-ylphenyl)methanamine |
| 3FUD |
2.2 |
Leukotriene A4 hydrolase in complex with N-methyl-1-(2-thiophen-2-ylphenyl)methanamine |
| 3FUE |
2.38 |
Leukotriene A4 hydrolase in complex with fragment 5-chloroindole and bestatin |
| 3FUF |
2.6 |
Leukotriene A4 hydrolase in complex with fragment 5-fluoroindole and bestatin |
| 3FUH |
1.8 |
Leukotriene A4 hydrolase in complex with fragment 5-hydroxyindole and bestatin |
| 3FUI |
2.2 |
Leukotriene A4 hydrolase in complex with N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline |
| 3FUJ |
1.9 |
Leukotriene A4 hydrolase in complex with 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole |
| 3FUK |
1.95 |
Leukotriene A4 hydrolase in complex with 1-[2-(1H-indol-5-yloxy)ethyl]piperidine-4-carboxylic acid |
| 3FUL |
2.39 |
Leukotriene A4 hydrolase in complex with pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone |
| 3FUM |
2.15 |
Leukotriene A4 hydrolase in complex with (R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanol |
| 3FUN |
1.58 |
Leukotriene A4 hydrolase in complex with {4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone |
| 3U9W |
1.25 |
Structure of human Leukotriene A4 hydrolase in complex with inhibitor sc57461A |
| 4DPR |
2.02 |
Structure of human Leukotriene A4 hydrolase in complex with inhibitor captopril |
| 4L2L |
1.648 |
Human Leukotriene A4 Hydrolase complexed with ligand 4-(4-benzylphenyl)thiazol-2-amine |
| 4MKT |
1.618 |
Human Leukotriene A4 Hydrolase in complex with Pro-Gly-Pro analogue and 4-(4-benzylphenyl)thiazol-2-amine |
| 4MS6 |
1.72 |
Human Leukotriene A4 Hydrolase in complex with Pro-Gly-Pro analogue |
| 4R7L |
1.66 |
Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1 |
| 4RSY |
1.93 |
Crystal structures of the Human leukotriene A4 Hydrolase complex with a potential inhibitor H7 |
| 4RVB |
1.93 |
Crystal Structure Analysis of the Human Leukotriene A4 Hydrolase |
| 5AEN |
1.864 |
Structure of human Leukotriene A4 hydrolase in complex with inhibitor dimethyl(2- (4-phenoxyphenoxy)ethyl)amine |
| 5BPP |
2.03 |
Structure of human Leukotriene A4 hydrolase in complex with inhibitor 4AZ |
| 5FWQ |
2.047 |
Apo structure of human Leukotriene A4 hydrolase |
| 5N3W |
2.3 |
Crystal structure of LTA4H bound to a selective inhibitor against LTB4 generation |
| 5NI2 |
1.501 |
Crystal structure of human LTA4H mutant E271A in complex with LTA4 (crystal form I) |
| 5NI4 |
1.895 |
Crystal structure of human LTA4H mutant E271A in complex with LTA4 (crystal form II) |
| 5NI6 |
1.54 |
Crystal structure of human LTA4H mutant D375N in complex with LTA4 |
| 5NIA |
1.764 |
Crystal structure of human LTA4H mutant D375N in open conformation (crystal form I) |
| 5NID |
1.568 |
Crystal structure of human LTA4H mutant D375N in open conformation (crystal form II) |
| 5NIE |
2.603 |
Crystal structure of human LTA4H mutant R563A in open conformation |
| 6ENB |
1.84 |
LTA4 hydrolase (E297Q) mutant in complex with Pro-Gly-Pro peptide |
| 6ENC |
1.95 |
LTA4 hydrolase in complex with Compound11 |
| 6END |
2.24 |
LTA4 hydrolase in complex with Compound15 |
| 6O5H |
2.84 |
The effect of modifier structure on the activation of leukotriene A4 hydrolase aminopeptidase activity. |
| 7AUZ |
1.9 |
LTA4 hydrolase in complex with compound LYS006 |
| 7AV0 |
1.9 |
LTA4 hydrolase in complex with compound R(13) |
| 7AV1 |
1.79 |
LTA4 hydrolase in complex with fragment2 |
| 7AV2 |
1.95 |
LTA4 hydrolase in complex with fragment1 |
| 7KZE |
2.9 |
Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity |
| 7LLQ |
2.85 |
Substrate-dependent divergence of leukotriene A4 hydrolase aminopeptidase activity |
