Summary of P11586

Gene: MTHFD1, MTHFC, MTHFD
Protein: C-1-tetrahydrofolate synthase, cytoplasmic


Protein family
Protein sequence
Protein function

Catalytic activity
EC number EC number description
1.5.1.5 Oxidoreductases; Acting on the CH-NH group of donors; With NAD+ or NADP+ as acceptor; methylenetetrahydrofolate dehydrogenase (NADP+)
3.5.4.9 Hydrolases; Acting on carbon-nitrogen bonds, other than peptide bonds; In cyclic amidines; methenyltetrahydrofolate cyclohydrolase
6.3.4.3 Ligases; Forming carbon-nitrogen bonds; Other carbon-nitrogen ligases; formate—tetrahydrofolate ligase
Publications

Structure

GO term

InterPro / Pfam

Reactome

Subcellular location

Interactor | Variant | Drug

Phenotype

Tissue and cell type

Disease