1YQ7 |
2.2 |
Human farnesyl diphosphate synthase complexed with risedronate |
1YV5 |
2.0 |
Human farnesyl diphosphate synthase complexed with Mg and risedronate |
1ZW5 |
2.3 |
X-ray structure of Farnesyl diphosphate synthase protein |
2F7M |
2.3 |
Crystal Structure of Unliganded Human FPPS |
2F89 |
2.6 |
Crystal structure of human FPPS in complex with pamidronate |
2F8C |
2.2 |
Crystal structure of FPPS in complex with Zoledronate |
2F8Z |
2.6 |
Crystal structure of human FPPS in complex with zoledronate and isopentenyl diphosphate |
2F92 |
2.15 |
Crystal structure of human FPPS in complex with alendronate |
2F94 |
1.94 |
Crystal structure of human FPPS in complex with ibandronate |
2F9K |
2.06 |
Crystal structure of human FPPS in complex with Zoledronate and Zn2+ |
2OPM |
2.4 |
Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-461 |
2OPN |
2.7 |
Human Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-527 |
2QIS |
1.8 |
Crystal structure of human farnesyl pyrophosphate synthase T210S mutant bound to risedronate |
2RAH |
2.0 |
Human FDPS synthase in complex with novel inhibitor |
2VF6 |
2.1 |
Human FDPS synthase in complex with minodronate |
3B7L |
1.95 |
Human farnesyl diphosphate synthase complexed with MG and minodronate |
3CP6 |
1.95 |
Crystal structure of human farnesyl diphosphate synthase (T201A mutant) complexed with Mg and biphosphonate inhibitor |
3N1V |
2.18 |
Human FPPS COMPLEX WITH FBS_01 |
3N1W |
2.56 |
Human FPPS COMPLEX WITH FBS_02 |
3N3L |
2.74 |
Human FPPS complex with FBS_03 |
3N45 |
1.88 |
Human FPPS complex with FBS_04 and zoledronic acid/MG2+ |
3N46 |
2.35 |
Human FPPS complex with NOV_980 and zoledronic acid/MG2+ |
3N49 |
2.5 |
Human FPPS COMPLEX WITH NOV_292 |
3N5H |
2.2 |
Human fpps complex with NOV_304 |
3N5J |
2.35 |
Human fpps complex with NOV_311 |
3N6K |
2.25 |
Human FPPS complex with NOV_823 |
3RYE |
2.1 |
Human FDPS Synthase in Complex with a N-Methyl Pyridinum Bisphosphonate |
3S4J |
1.95 |
Human FDPS Synthase in Complex with a Rigid Analog of Risedronate |
4DEM |
1.85 |
Crystal structure of human FPPS in complex with YS_04_70 |
4GA3 |
2.39 |
Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1260 |
4H5C |
2.02 |
Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate |
4H5D |
2.02 |
Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate |
4H5E |
2.04 |
Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate |
4JVJ |
2.8 |
Crystal structure of human FPPS in complex with magnesium, CL01131, and sulfate |
4KFA |
1.98 |
Crystal structure of human farnesyl pyrophosphate synthase (t201a mutant) complexed with mg and zoledronate |
4KPD |
1.96 |
Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate |
4KPJ |
1.95 |
Crystal Structure of Farnesyl Pyrophosphate Synthase (Y204A) Mutant complexed with Mg, Pamidronate |
4KQ5 |
2.4 |
Crystal Structure of Human Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg and Zoledronate |
4KQS |
1.97 |
Crystal Structure of Farnesyl Pyrophosphate Synthase Mutant (Y204A) Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate |
4KQU |
2.07 |
Crystal Structure of Farnesyl Synthase Mutant (Y204A) Complexed with Mg, Alendronate and Isopentenyl Pyrophosphate |
4L2X |
2.55 |
Crystal structure of human FPPS in complex with magnesium, CL02134, and inorganic pyrophosphate |
4LFV |
2.0 |
Crystal structure of human FPPS in complex with YS0470 and two molecules of inorganic phosphate |
4LPG |
2.35 |
Crystal structure of human FPPS in complex with CL01131 |
4LPH |
2.3 |
Crystal structure of human FPPS in complex with CL03093 |
4N1Z |
2.35 |
Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1222 |
4N9U |
2.11 |
The role of lysine 200 in the human farnesyl pyrophosphate synthase catalytic mechanism and the mode of inhibition by the nitrogen-containing bisphosphonates |
4NFI |
1.85 |
Crystal structure of human FPPS in complex with magnesium and JDS05120 |
4NFJ |
2.05 |
Crystal structure of human FPPS in complex with magnesium, JDS05120, and sulfate |
4NFK |
1.85 |
Crystal structure of human FPPS in complex with nickel, JDS05120, and sulfate |
4NG6 |
2.35 |
The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates |
4NKE |
1.46 |
The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates |
4NKF |
2.0 |
The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates |
4NUA |
1.43 |
The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates |
4OGU |
2.1 |
The effects of Lysine 200 and Phenylalanine 239 Farnesyl Pyrophosphate Synthase (FPPS) mutations on the catalytic activity, crystal structure and inhibition by nitrogen containing bisphosphonates |
4P0V |
2.4 |
Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione |
4P0W |
2.406 |
Human farnesyl diphosphate synthase in complex with Arenarone and zoledronate |
4P0X |
2.5 |
Human farnesyl diphosphate synthase in complex with Taxodione |
4PVX |
2.18 |
Crystal structure of human FPPS in complex with [({4-[4-(cyclopropyloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid) |
4PVY |
2.05 |
Crystal structure of human FPPS in complex with [({5-[4-(propan-2-yloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid) |
4Q23 |
1.98 |
The role of threonine 201 and tyrosine 204 in the human farnesyl pyrophosphate synthase catalytic mechanism and the mode of inhibition by the nitrogen-containing bisphosphonates |
4QPF |
1.59 |
New lower bone affinity bisphosphonate drug design for effective use in diseases characterized by abnormal bone resorption |
4QXS |
1.9 |
Crystal structure of human FPPS in complex with WC01088 |
4RXA |
2.2 |
Crystal structure of human farnesyl diphosphate synthase in complex with BPH-1358 |
4XQR |
2.15 |
Crystal structure of unliganded human FPPS at 2.15 angstrom resolution |
4XQS |
2.3 |
Crystal structure of human FPPS in complex with one magnesium ion |
4XQT |
2.1 |
Crystal structure of human FPPS in complex with three magnesium ions |
5CG5 |
1.402 |
Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate |
5CG6 |
1.7 |
Neutron crystal structure of human farnesyl pyrophosphate synthase in complex with risedronate and isopentenyl pyrophosphate |
5DGM |
2.86 |
Crystal structure of human FPPS in complex with monophosphonate compound 7 |
5DGN |
2.08 |
Crystal structure of human FPPS in complex with compound 13 |
5DGS |
2.62 |
Crystal structure of human FPPS in complex with the monophosphonate compound 15 |
5DIQ |
2.1 |
Crystal structure of human FPPS in complex with salicylic acid derivative 3a |
5DJP |
2.4 |
Crystal structure of human FPPS in complex with biaryl compound 5 |
5DJR |
2.4 |
Crystal structure of human FPPS in complex with biaryl compound 6 |
5DJV |
2.3 |
Crystal structure of human FPPS in complex with biaryl compound 8e |
5JA0 |
1.9 |
Crystal structure of human FPPS with allosterically bound FPP |
5JUZ |
2.4 |
Crystal structure of human FPPS in complex with an allosteric inhibitor CL-06-057 |
5JV0 |
2.4 |
Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-038 |
5JV1 |
2.3 |
Crystal structure of human FPPS in complex with an allosteric inhibitor CL-08-066 |
5JV2 |
2.3 |
Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-055 |
5KSX |
2.65 |
Crystal structure of human FPPS in complex with an allosteric inhibitor AM-02-072 |
5YGI |
2.177 |
Crystal structure of human FPPS in complex with an inhibitor THZ93 |
6N7Y |
2.0 |
Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-102 |
6N7Z |
2.55 |
Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 |
6N82 |
2.0 |
Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 |
6N83 |
2.0 |
Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02037 |
6OAG |
2.3 |
Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02-82 |
6OAH |
2.2 |
Crystal structure of human FPPS in complex with an allosteric inhibitor YF-02-78 |