Protein family
The protein has not catalytic activity
Protein sequence
Protein function
Publications
Catalytic activity
GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0001525 | angiogenesis |
| Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus |
| Biological Process | GO:1990830 | cellular response to leukemia inhibitory factor |
| Biological Process | GO:0046627 | negative regulation of insulin receptor signaling pathway |
| Biological Process | GO:0017148 | negative regulation of translation |
| Biological Process | GO:0048026 | positive regulation of mRNA splicing, via spliceosome |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:1901838 | positive regulation of transcription of nucleolar large rRNA by RNA polymerase I |
| Biological Process | GO:0050730 | regulation of peptidyl-tyrosine phosphorylation |
| Molecular Function | GO:0044547 | DNA topoisomerase binding |
| Molecular Function | GO:0042731 | PH domain binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0043560 | insulin receptor substrate binding |
| Molecular Function | GO:0048027 | mRNA 5'-UTR binding |
| Molecular Function | GO:0042162 | telomeric DNA binding |
| Cellular Component | GO:0005938 | cell cortex |
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0001533 | cornified envelope |
| Cellular Component | GO:0036464 | cytoplasmic ribonucleoprotein granule |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0005681 | spliceosomal complex |
| InterPro
|
InterPro name |
|---|---|
| IPR000504 | RNA recognition motif domain |
| IPR003954 | RNA recognition motif domain, eukaryote |
| IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| IPR034230 | Nucleolin, RNA recognition motif 1 |
| IPR034233 | Nucleolin, RNA recognition motif 2 |
| IPR034234 | Nucleolin, RNA recognition motif 3 |
| IPR034235 | Nucleolin, RNA recognition motif 4 |
| IPR035979 | RNA-binding domain superfamily |
| Pfam
|
Pfam name |
|---|---|
| PF00076 | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-6791226 | Major pathway of rRNA processing in the nucleolus and cytosol | Leaf | R-HSA-8953854 | Metabolism of RNA |
| HPO ID
|
HPO name |
|---|
| Tissue
|
Cell type
|
Expression level | Reliability |
|---|---|---|---|
| adipose tissue | adipocytes | High | Supported |
| adrenal gland | glandular cells | High | Supported |
| appendix | endocrine cells | High | Supported |
| appendix | enterocytes | High | Supported |
| appendix | goblet cells | High | Supported |
| appendix | non-germinal center cells | High | Supported |
| bone marrow | hematopoietic cells | High | Supported |
| breast | adipocytes | High | Supported |
| breast | glandular cells | High | Supported |
| breast | myoepithelial cells | High | Supported |
| bronchus | respiratory epithelial cells | High | Supported |
| caudate | glial cells | High | Supported |
| caudate | neuronal cells | High | Supported |
| cerebellum | Purkinje cells | High | Supported |
| cerebellum | cells in granular layer | High | Supported |
| cerebellum | cells in molecular layer | High | Supported |
| cerebral cortex | endothelial cells | Medium | Supported |
| cerebral cortex | glial cells | High | Supported |
| cerebral cortex | neuronal cells | High | Supported |
| cervix | glandular cells | High | Supported |
| cervix | squamous epithelial cells | High | Supported |
| colon | endocrine cells | High | Supported |
| colon | endothelial cells | High | Supported |
| colon | enterocytes | High | Supported |
| colon | fibroblasts | High | Supported |
| colon | goblet cells | High | Supported |
| colon | mucosal lymphoid cells | High | Supported |
| duodenum | endocrine cells | High | Supported |
| duodenum | enterocytes | High | Supported |
| duodenum | goblet cells | High | Supported |
| duodenum | paneth cells | High | Supported |
| endometrium 1 | cells in endometrial stroma | High | Supported |
| endometrium 1 | glandular cells | High | Supported |
| endometrium 2 | cells in endometrial stroma | High | Supported |
| endometrium 2 | glandular cells | High | Supported |
| epididymis | glandular cells | High | Supported |
| esophagus | squamous epithelial cells | High | Supported |
| fallopian tube | glandular cells | High | Supported |
| gallbladder | glandular cells | High | Supported |
| heart muscle | cardiomyocytes | High | Supported |
| hippocampus | glial cells | High | Supported |
| hippocampus | neuronal cells | High | Supported |
| kidney | cells in glomeruli | High | Supported |
| kidney | cells in tubules | High | Supported |
| liver | cholangiocytes | High | Supported |
| liver | hepatocytes | High | Supported |
| lung | alveolar cells type I | High | Supported |
| lung | alveolar cells type II | High | Supported |
| lung | endothelial cells | High | Supported |
| lung | macrophages | High | Supported |
| lymph node | germinal center cells | High | Supported |
| lymph node | non-germinal center cells | High | Supported |
| nasopharynx | respiratory epithelial cells | High | Supported |
| oral mucosa | squamous epithelial cells | High | Supported |
| ovary | follicle cells | High | Supported |
| ovary | ovarian stroma cells | High | Supported |
| pancreas | exocrine glandular cells | High | Supported |
| pancreas | pancreatic endocrine cells | High | Supported |
| parathyroid gland | glandular cells | High | Supported |
| placenta | decidual cells | High | Supported |
| placenta | trophoblastic cells | High | Supported |
| prostate | glandular cells | High | Supported |
| rectum | endocrine cells | High | Supported |
| rectum | endothelial cells | High | Supported |
| rectum | enterocytes | High | Supported |
| rectum | fibroblasts | High | Supported |
| rectum | goblet cells | High | Supported |
| rectum | mucosal lymphoid cells | High | Supported |
| rectum | peripheral nerve/ganglion | High | Supported |
| salivary gland | glandular cells | High | Supported |
| seminal vesicle | glandular cells | High | Supported |
| skeletal muscle | myocytes | High | Supported |
| skin 1 | cells in basal layer | High | Supported |
| skin 1 | cells in granular layer | High | Supported |
| skin 1 | cells in spinous layer | High | Supported |
| skin 1 | eccrine glands | High | Supported |
| skin 1 | endothelial cells | High | Supported |
| skin 1 | fibrohistiocytic cells | High | Supported |
| skin 1 | hair follicles | High | Supported |
| skin 1 | langerhans cells | High | Supported |
| skin 1 | lymphocytes | High | Supported |
| skin 1 | melanocytes | High | Supported |
| skin 1 | vascular mural cells | High | Supported |
| skin 2 | cells in basal layer | High | Supported |
| skin 2 | cells in granular layer | High | Supported |
| skin 2 | cells in spinous layer | High | Supported |
| skin 2 | endothelial cells | High | Supported |
| skin 2 | fibrohistiocytic cells | High | Supported |
| skin 2 | hair follicles | High | Supported |
| skin 2 | langerhans cells | High | Supported |
| skin 2 | lymphocytes | High | Supported |
| skin 2 | melanocytes | High | Supported |
| skin 2 | vascular mural cells | High | Supported |
| small intestine | endocrine cells | High | Supported |
| small intestine | enterocytes | High | Supported |
| small intestine | goblet cells | High | Supported |
| small intestine | paneth cells | High | Supported |
| smooth muscle | smooth muscle cells | High | Supported |
| soft tissue 1 | chondrocytes | High | Supported |
| soft tissue 1 | fibroblasts | High | Supported |
| soft tissue 1 | peripheral nerve | High | Supported |
| soft tissue 2 | fibroblasts | High | Supported |
| soft tissue 2 | peripheral nerve | High | Supported |
| spleen | cells in red pulp | High | Supported |
| spleen | cells in white pulp | High | Supported |
| stomach 1 | glandular cells | High | Supported |
| stomach 2 | glandular cells | High | Supported |
| testis | Leydig cells | High | Supported |
| testis | pachytene spermatocytes | High | Supported |
| testis | peritubular cells | High | Supported |
| testis | preleptotene spermatocytes | High | Supported |
| testis | round or early spermatids | High | Supported |
| testis | sertoli cells | High | Supported |
| testis | spermatogonia cells | High | Supported |
| thyroid gland | glandular cells | High | Supported |
| tonsil | germinal center cells | High | Supported |
| tonsil | non-germinal center cells | High | Supported |
| tonsil | squamous epithelial cells | High | Supported |
| urinary bladder | urothelial cells | High | Supported |
| vagina | squamous epithelial cells | High | Supported |
| Disease name | MONDO ID
|
ICD10
|
ICD10 chapter
|
OMIM
|
Orphanet
|
|---|