Protein family
The protein has not catalytic activity
Protein sequence
Protein function
Publications
Catalytic activity
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 7UX2 | 2.9 | cryo-EM structure of the Raptor-TFEB-Rag-Ragulator complex |
| 7UXC | 3.2 | cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion |
| 7UXH | 3.2 | cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex |
| 7Y62 | 2.0 | Crystal structure of human TFEB HLHLZ domain |
GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0002250 | adaptive immune response |
| Biological Process | GO:0140367 | antibacterial innate immune response |
| Biological Process | GO:0006914 | autophagy |
| Biological Process | GO:0034198 | cellular response to amino acid starvation |
| Biological Process | GO:0009267 | cellular response to starvation |
| Biological Process | GO:0001892 | embryonic placenta development |
| Biological Process | GO:0006959 | humoral immune response |
| Biological Process | GO:0032418 | lysosome localization |
| Biological Process | GO:0007040 | lysosome organization |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:0010508 | positive regulation of autophagy |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006355 | regulation of DNA-templated transcription |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0046983 | protein dimerization activity |
| Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding |
| Molecular Function | GO:0000976 | transcription cis-regulatory region binding |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005765 | lysosomal membrane |
| Cellular Component | GO:0005634 | nucleus |
| InterPro
|
InterPro name |
|---|---|
| IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| IPR021802 | MiT/TFE transcription factors, C-terminal |
| IPR024098 | Transcription factor EB, bHLHzip domain |
| IPR031867 | MiT/TFE transcription factors, N-terminal |
| IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
| Pfam
|
Pfam name |
|---|---|
| PF00010 | Helix-loop-helix DNA-binding domain |
| PF11851 | Domain of unknown function (DUF3371) |
| PF15951 | MITF/TFEB/TFEC/TFE3 N-terminus |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|
| HPO ID
|
HPO name |
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| Tissue
|
Cell type
|
Expression level | Reliability |
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| Disease name | MONDO ID
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ICD10
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ICD10 chapter
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OMIM
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Orphanet
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