| 1MEJ |
2.0 |
Human Glycinamide Ribonucleotide Transformylase domain at pH 8.5 |
| 1MEN |
2.23 |
complex structure of human GAR Tfase and substrate beta-GAR |
| 1MEO |
1.72 |
human glycinamide ribonucleotide Transformylase at pH 4.2 |
| 1NJS |
1.98 |
human GAR Tfase in complex with hydrolyzed form of 10-trifluoroacetyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid |
| 1RBM |
2.3 |
Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid |
| 1RBQ |
2.104 |
Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid |
| 1RBY |
2.101 |
Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid and substrate beta-GAR |
| 1RBZ |
2.1 |
Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid |
| 1RC0 |
2.05 |
Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid |
| 1RC1 |
2.25 |
Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid |
| 1ZLX |
2.2 |
The apo structure of human glycinamide ribonucleotide transformylase |
| 1ZLY |
2.07 |
The structure of human glycinamide ribonucleotide transformylase in complex with alpha,beta-N-(hydroxyacetyl)-D-ribofuranosylamine and 10-formyl-5,8,dideazafolate |
| 2QK4 |
2.45 |
Human glycinamide ribonucleotide synthetase |
| 2V9Y |
2.1 |
Human aminoimidazole ribonucleotide synthetase |
| 4EW1 |
1.522 |
High resolution structure of human glycinamide ribonucleotide transformylase in apo form. |
| 4EW2 |
1.602 |
The structure of human glycinamide ribonucleotide transformylase in complex with 10S-methylthio-DDATHF. |
| 4EW3 |
1.702 |
The structure of human glycinamide ribonucleotide transformylase in complex with 10R-methylthio-DDATHF. |
| 4ZYT |
1.702 |
Human GAR transformylase in complex with GAR and N-{4-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)benzyl]benzoyl}-L-glutamic acid (AGF23) |
| 4ZYU |
1.95 |
Human GAR transformylase in complex with GAR and N-{4-[4-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)-butyl]benzoyl}-L-glutamic acid (AGF50) |
| 4ZYV |
2.053 |
Human GAR transformylase in complex with GAR and N-({5-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)butyl]thiophen-2-yl}carbonyl)-L-glutamic acid (AGF71) |
| 4ZYW |
2.05 |
Human GAR transformylase in complex with GAR and N-({5-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)propyl]thiophen-2-yl}carbonyl)-L-glutamic acid (AGF94) |
| 4ZYX |
1.65 |
Human GAR transformylase in complex with GAR and (S)-2-({4-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)butyl]thiophene-2-carbonyl}amino)pentanedioic acid (AGF117) |
| 4ZYY |
1.85 |
Human GAR transformylase in complex with GAR and (S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)butyl]thiophene-3-carbonyl}amino)pentanedioic acid (AGF118) |
| 4ZYZ |
1.6 |
Human GAR transformylase in complex with GAR and (S)-2-(7-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)heptanamido)pentanedioic acid (AGF145) |
| 4ZZ0 |
1.65 |
Human GAR transformylase in complex with GAR and (S)-2-(8-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)octanamido)pentanedioic acid (AGF147) |
| 4ZZ1 |
1.351 |
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({4-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-2-CARBONYL}-AMINO)-PENTANEDIOIC ACID |
| 4ZZ2 |
1.451 |
HUMAN GAR TRANSFORMYLASE IN COMPLEX WITH GAR AND (S)-2-({5-[3-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-6-YL)-PROPYL]-THIOPHENE-3-CARBONYL}-AMINO)-PENTANEDIOIC ACID |
| 4ZZ3 |
2.504 |
Human GAR transformylase in complex with GAR and pemetrexed |
| 5J9F |
2.1 |
Human GAR transformylase in complex with GAR and (4-{[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl]amino}benzoyl)-L-glutamic acid (AGF183) |
| 7JG0 |
1.984 |
Human GAR transformylase in complex with GAR substrate and AGF102 inhibitor |
| 7JG3 |
2.091 |
Human GAR transformylase in complex with GAR substrate and AGF103 inhibitor |
| 7JG4 |
2.455 |
Human GAR transformylase in complex with GAR substrate and AGF131 inhibitor |
