Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
2.7.4.10
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor;
nucleoside-triphosphate—adenylate kinase
2.7.4.6
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor;
nucleoside-diphosphate kinase
GO ontology | GO term | GO description |
---|---|---|
Biological Process | GO:0006172 | ADP biosynthetic process |
Biological Process | GO:0046033 | AMP metabolic process |
Biological Process | GO:0046034 | ATP metabolic process |
Biological Process | GO:0046039 | GTP metabolic process |
Biological Process | GO:0071456 | cellular response to hypoxia |
Biological Process | GO:0015949 | nucleobase-containing small molecule interconversion |
Biological Process | GO:0009142 | nucleoside triphosphate biosynthetic process |
Biological Process | GO:0016310 | phosphorylation |
Biological Process | GO:0002082 | regulation of oxidative phosphorylation |
Biological Process | GO:0009188 | ribonucleoside diphosphate biosynthetic process |
Molecular Function | GO:0005524 | ATP binding |
Molecular Function | GO:0005525 | GTP binding |
Molecular Function | GO:0004017 | adenylate kinase activity |
Molecular Function | GO:0004550 | nucleoside diphosphate kinase activity |
Molecular Function | GO:0050145 | nucleoside monophosphate kinase activity |
Molecular Function | GO:0046899 | nucleoside triphosphate adenylate kinase activity |
Cellular Component | GO:0005737 | cytoplasm |
Cellular Component | GO:0005759 | mitochondrial matrix |
Cellular Component | GO:0005739 | mitochondrion |
InterPro | InterPro name |
---|---|
IPR000850 | Adenylate kinase/UMP-CMP kinase |
IPR006259 | Adenylate kinase subfamily |
IPR007862 | Adenylate kinase, active site lid domain |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
IPR028585 | Adenylate kinase 4, mitochondrial |
IPR028586 | Adenylate kinase 3/4, mitochondrial |
IPR033690 | Adenylate kinase, conserved site |
IPR036193 | Adenylate kinase, active site lid domain superfamily |
Pfam | Pfam name |
---|---|
PF00406 | Adenylate kinase |
PF05191 | Adenylate kinase, active site lid |
Reactome | Reactome Name | Node type | Reactome Root | Reactome Root Name |
---|---|---|---|---|
R-HSA-499943 | Interconversion of nucleotide di- and triphosphates | Leaf | R-HSA-1430728 | Metabolism |
Location | ECO term | Pubmed |
---|---|---|
Mitochondrion matrix | ECO:0000255 | PubMed:11485571 |
Mitochondrion matrix | ECO:0000255 | PubMed:19766732 |
Mitochondrion matrix | ECO:0000255 | PubMed:26980435 |