Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
1.11.1.27
Oxidoreductases;
Acting on a peroxide as acceptor;
Peroxidases;
glutathione-dependent peroxiredoxin
2.3.1.23
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups;
1-acylglycerophosphocholine O-acyltransferase
3.1.1.4
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases;
phospholipase A2
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0045454 | cell redox homeostasis |
| Biological Process | GO:0098869 | cellular oxidant detoxification |
| Biological Process | GO:0046475 | glycerophospholipid catabolic process |
| Biological Process | GO:0048026 | positive regulation of mRNA splicing, via spliceosome |
| Biological Process | GO:0006979 | response to oxidative stress |
| Molecular Function | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity |
| Molecular Function | GO:0045296 | cadherin binding |
| Molecular Function | GO:0047499 | calcium-independent phospholipase A2 activity |
| Molecular Function | GO:0004602 | glutathione peroxidase activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0051920 | peroxiredoxin activity |
| Molecular Function | GO:0004623 | phospholipase A2 activity |
| Molecular Function | GO:0031625 | ubiquitin protein ligase binding |
| Cellular Component | GO:0035578 | azurophil granule lumen |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| InterPro
|
InterPro name |
|---|---|
| IPR000866 | Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant |
| IPR013766 | Thioredoxin domain |
| IPR019479 | Peroxiredoxin, C-terminal |
| IPR024706 | Peroxiredoxin, AhpC-type |
| IPR036249 | Thioredoxin-like superfamily |
| IPR045020 | 1-Cys peroxiredoxin |
| Pfam
|
Pfam name |
|---|---|
| PF00578 | AhpC/TSA family |
| PF10417 | C-terminal domain of 1-Cys peroxiredoxin |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-3299685 | Detoxification of Reactive Oxygen Species | Leaf | R-HSA-8953897 | Cellular responses to stimuli |
| R-HSA-6798695 | Neutrophil degranulation | Leaf | R-HSA-168256 | Immune System |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Cytoplasm | ECO:0000269 | PubMed:16186110 |
| Cytoplasm | ECO:0000269 | PubMed:19188445 |
| Cytoplasm | ECO:0000269 | PubMed:9497358 |
| Lysosome | ECO:0000250 |