Protein family
The protein has not catalytic activity
Protein sequence
Protein function
Catalytic activity
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 4V6X | 5.0 | Structure of the human 80S ribosome |
| 5A8L | 3.8 | Human eRF1 and the hCMV nascent peptide in the translation termination complex |
| 5AJ0 | 3.5 | Cryo electron microscopy of actively translating human polysomes (POST state). |
| 6OLG | 3.4 | Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA) |
| 6ZM7 | 2.7 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex |
| 6ZME | 3.0 | SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex |
| 6ZMI | 2.6 | SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex |
| 6ZMO | 3.1 | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex |
| 7VB2 | Solution structure of human ribosomal protein uL11 |
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0002181 | cytoplasmic translation |
| Biological Process | GO:0006412 | translation |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0070180 | large ribosomal subunit rRNA binding |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0022625 | cytosolic large ribosomal subunit |
| Cellular Component | GO:0022626 | cytosolic ribosome |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005925 | focal adhesion |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0014069 | postsynaptic density |
| InterPro
|
InterPro name |
|---|---|
| IPR000911 | Ribosomal protein L11/L12 |
| IPR020783 | Ribosomal protein L11, C-terminal |
| IPR020784 | Ribosomal protein L11, N-terminal |
| IPR020785 | Ribosomal protein L11, conserved site |
| IPR036769 | Ribosomal protein L11, C-terminal domain superfamily |
| IPR036796 | Ribosomal protein L11/L12, N-terminal domain superfamily |
| Pfam
|
Pfam name |
|---|---|
| PF00298 | Ribosomal protein L11, RNA binding domain |
| PF03946 | Ribosomal protein L11, N-terminal domain |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-156827 | L13a-mediated translational silencing of Ceruloplasmin expression | Leaf | R-HSA-392499 | Metabolism of proteins |
| R-HSA-156902 | Peptide chain elongation | Leaf | R-HSA-392499 | Metabolism of proteins |
| R-HSA-1799339 | SRP-dependent cotranslational protein targeting to membrane | Leaf | R-HSA-392499 | Metabolism of proteins |
| R-HSA-192823 | Viral mRNA Translation | Leaf | R-HSA-1643685 | Disease |
| R-HSA-2408557 | Selenocysteine synthesis | Leaf | R-HSA-1430728 | Metabolism |
| R-HSA-6791226 | Major pathway of rRNA processing in the nucleolus and cytosol | Leaf | R-HSA-8953854 | Metabolism of RNA |
| R-HSA-72689 | Formation of a pool of free 40S subunits | Leaf | R-HSA-392499 | Metabolism of proteins |
| R-HSA-72706 | GTP hydrolysis and joining of the 60S ribosomal subunit | Leaf | R-HSA-392499 | Metabolism of proteins |
| R-HSA-72764 | Eukaryotic Translation Termination | Leaf | R-HSA-392499 | Metabolism of proteins |
| R-HSA-9010553 | Regulation of expression of SLITs and ROBOs | Leaf | R-HSA-1266738 | Developmental Biology |
| R-HSA-9633012 | Response of EIF2AK4 (GCN2) to amino acid deficiency | Leaf | R-HSA-8953897 | Cellular responses to stimuli |
| R-HSA-975956 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | Leaf | R-HSA-8953854 | Metabolism of RNA |
| R-HSA-975957 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | Leaf | R-HSA-8953854 | Metabolism of RNA |