Structure
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 4PVF | 2.6 | Crystal structure of Homo sapiens holo serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), isoform 3, transcript variant 5, 483 aa, at 2.6 ang. resolution |
| 5V7I | 2.47 | Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile |
| 5X3V | 2.85 | Structure of human SHMT2 protein mutant |
| 6DK3 | 2.04 | HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2 |
| 6H3C | 3.9 | Cryo-EM structure of the BRISC complex bound to SHMT2 |
| 6M5O | 2.30001 | Co-crystal structure of human serine hydroxymethyltransferase 2 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid |
| 6QVG | 2.32 | Human SHMT2 in complex with lometrexol |
| 6QVL | 2.28 | Human SHMT2 in complex with pemetrexed |
| 6R8F | 3.8 | Cryo-EM structure of the Human BRISC-SHMT2 complex |
| 7BYI | 2.76 | Structure of SHMT2 in complex with CBX |
| 8AQL | 1.23 | High-resolution crystal structure of human SHMT2 |
