| 1IRY |
|
Solution structure of the hMTH1, a nucleotide pool sanitization enzyme |
| 3Q93 |
1.8 |
Crystal Structure of Human 8-oxo-dGTPase (MTH1) |
| 3WHW |
2.701 |
MTH1 in complex with Ruthenium-based inhibitor |
| 3ZR0 |
1.8 |
Crystal structure of human MTH1 in complex with 8-oxo-dGMP |
| 3ZR1 |
1.9 |
Crystal structure of human MTH1 |
| 4C9W |
1.65 |
Crystal structure of NUDT1 (MTH1) with R-crizotinib |
| 4C9X |
1.2 |
Crystal structure of NUDT1 (MTH1) with S-crizotinib |
| 4N1T |
1.6 |
Structure of human MTH1 in complex with TH287 |
| 4N1U |
1.6 |
Structure of human MTH1 in complex with TH588 |
| 5ANS |
1.6 |
Potent and selective inhibitors of MTH1 probe its role in cancer cell survival |
| 5ANT |
2.0 |
Potent and selective inhibitors of MTH1 probe its role in cancer cell survival |
| 5ANU |
1.8 |
MTH1 in complex with compound 15 |
| 5ANV |
1.16 |
MTH1 in complex with compound 15 |
| 5ANW |
1.37 |
MTH1 in complex with compound 24 |
| 5FSI |
1.63 |
MTH1 substrate recognition: Complex with 8-oxo-dGTP. |
| 5FSK |
1.56 |
MTH1 substrate recognition: Complex with 8-oxo-dGTP. |
| 5FSL |
1.24 |
MTH1 substrate recognition: Complex with a methylaminopurinone |
| 5FSM |
1.67 |
MTH1 substrate recognition: Complex with a methylbenzimidazolyl acetamide. |
| 5FSN |
1.69 |
MTH1 substrate recognition: Complex with a aminomethylpyrimidinyl oxypropanol. |
| 5FSO |
1.67 |
MTH1 substrate recognition: Complex with a methylaminopyrimidinedione. |
| 5GHI |
1.211 |
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP |
| 5GHJ |
1.2 |
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP |
| 5GHM |
1.5 |
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 7.0 |
| 5GHN |
1.391 |
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP |
| 5GHO |
1.191 |
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 8-oxo-dGTP |
| 5GHP |
1.192 |
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP |
| 5GHQ |
1.181 |
Crystal structure of human MTH1(G2K/D120A mutant) in complex with 2-oxo-dATP under high concentrations of 2-oxo-dATP |
| 5NGR |
2.2 |
Crystal structure of human MTH1 in complex with fragment inhibitor 8-(methylsulfanyl)-7H-purin-6-amine |
| 5NGS |
1.85 |
Crystal structure of human MTH1 in complex with inhibitor 6-[(2-phenylethyl)sulfanyl]-7H-purin-2-amine |
| 5NGT |
1.54 |
Crystal structure of human MTH1 in complex with inhibitor 7-(furan-2-yl)-5-methyl-1,3-benzoxazol-2-amine |
| 5NHY |
1.72 |
BAY-707 in complex with MTH1 |
| 5OTM |
1.8 |
Crystal structure of human MTH1 in complex with O6-methyl-dGMP |
| 5WS7 |
1.0 |
Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP |
| 6AA3 |
2.001 |
Crystal structure of MTH1 in apo form (cocktail No. 1) |
| 6AA4 |
1.9 |
Crystal structure of MTH1 in complex with alpha-mangostin (cocktail No. 9) |
| 6AA5 |
1.901 |
Crystal structure of MTH1 in complex with 3-isomangostin |
| 6EQ2 |
1.802 |
MTH1 in complex with fragment 6 |
| 6EQ3 |
1.798 |
MTH1 in complex with fragment 9 |
| 6EQ4 |
1.4 |
MTH1 in complex with fragment 8 |
| 6EQ5 |
1.801 |
MTH1 in complex with fragment 4 |
| 6EQ6 |
2.002 |
MTH1 in complex with fragment 1 |
| 6EQ7 |
1.5 |
MTH1 in complex with fragment 11 |
| 6F1X |
1.9 |
Complex between MTH1 and compound 7 (a 7-azaindole-2-amide derivative) |
| 6F20 |
2.0 |
Complex between MTH1 and compound 1 (a 7-azaindole-4-ester derivative) |
| 6F22 |
1.55 |
Complex between MTH1 and compound 29 (a 4-amino-2,7-diazaindole derivative) |
| 6F23 |
1.84 |
Complex between MTH1 and compound 16 (a 4-amino-7-azaindole derivative) |
| 6GLE |
1.402 |
Crystal structure of hMTH1 in complex with TH scaffold 1 in the presence of acetate |
| 6GLF |
2.0 |
Crystal structure of hMTH1 F27A in the presence of acetate |
| 6GLG |
1.313 |
Crystal structure of hMTH1 F27A in complex with LW14 in the presence of acetate |
| 6GLH |
1.201 |
Crystal structure of hMTH1 F27A in complex with LW14 in the absence of acetate |
| 6GLI |
1.6 |
Crystal structure of hMTH1 F27A in complex with TH scaffold 1 in the presence of acetate |
| 6GLJ |
1.301 |
Crystal structure of hMTH1 F27A in complex with TH scaffold 1 in the absence of acetate |
| 6GLK |
1.5 |
Crystal structure of hMTH1 N33A in the presence of acetate |
| 6GLL |
1.395 |
Crystal structure of hMTH1 N33A in complex with LW14 in the presence of acetate |
| 6GLM |
1.6 |
Crystal structure of hMTH1 N33A in complex with LW14 in the absence of acetate |
| 6GLN |
1.401 |
Crystal structure of hMTH1 N33A in complex with TH scaffold 1 in the absence of acetate |
| 6GLO |
1.701 |
Crystal structure of hMTH1 N33G in the presence of acetate |
| 6GLP |
1.5 |
Crystal structure of hMTH1 N33G in complex with LW14 in the presence of acetate |
| 6GLQ |
1.601 |
Crystal structure of hMTH1 N33G in complex with LW14 in the absence of acetate |
| 6GLR |
1.601 |
Crystal structure of hMTH1 N33G in complex with TH scaffold 1 in the presence of acetate |
| 6GLS |
1.501 |
Crystal structure of hMTH1 N33G in complex with TH scaffold 1 in the absence of acetate |
| 6GLT |
1.596 |
Crystal structure of hMTH1 D120N in the presence of acetate |
| 6GLU |
1.7 |
Crystal structure of hMTH1 D120N in complex with LW14 in the presence of acetate |
| 6GLV |
1.601 |
Crystal structure of hMTH1 D120N in complex with TH scaffold 1 in the absence of acetate |
| 6IJY |
1.04 |
Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 8-oxo-dGTP determined using a crystal obtained under microgravity |
| 6ILI |
1.45 |
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 8-oxo-dGTP at pH 6.5 |
| 6IMZ |
2.1 |
Crystal structure of MTH1 in complex with 18-Crown-6 |
| 6JVF |
1.73 |
Crystal structure of human apo MTH1 |
| 6JVG |
1.844 |
Crystal structure of human MTH1 in complex with compound MI0639 |
| 6JVH |
2.04 |
Crystal structure of human MTH1 in complex with compound MI0320 |
| 6JVI |
2.249 |
Crystal structure of human MTH1 in complex with compound MI0861 |
| 6JVJ |
2.297 |
Crystal structure of human MTH1 in complex with compound MI1006 |
| 6JVK |
2.1 |
Crystal structure of human MTH1 in complex with compound MI1012 |
| 6JVL |
1.9 |
Crystal structure of human MTH1 in complex with compound MI1014 |
| 6JVM |
2.098 |
Crystal structure of human MTH1 in complex with compound MI1016 |
| 6JVN |
2.102 |
Crystal structure of human MTH1 in complex with compound MI1020 |
| 6JVO |
1.902 |
Crystal structure of human MTH1 in complex with compound MI1022 |
| 6JVP |
2.206 |
Crystal structure of human MTH1 in complex with compound MI1024 |
| 6JVQ |
2.197 |
Crystal structure of human MTH1 in complex with compound MI1025 |
| 6JVR |
2.295 |
Crystal structure of human MTH1 in complex with compound MI1026 |
| 6JVS |
2.1 |
Crystal structure of human MTH1 in complex with compound MI1029 |
| 6JVT |
1.801 |
Crystal structure of human MTH1 in complex with compound MI1030 |
| 6QVO |
2.45 |
Crystal structure of human MTH1 in complex with N6-methyl-dAMP |
| 6US2 |
1.80013 |
MTH1 in complex with compound 5 |
| 6US3 |
1.47029 |
MTH1 in complex with compound 4 |
| 6US4 |
1.95033 |
MTH1 in complex with compound 32 |
| 7ESF |
1.55 |
The Crystal Structure of human MTH1 from Biortus |
| 7N03 |
1.13 |
Crystal structure of MTH1 in complex with compound 31 |
| 7N13 |
1.59 |
Crystal structure of MTH1 in complex with compound 32 |
| 8I18 |
1.1 |
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 7.7 |
| 8I19 |
1.48 |
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 8.0 |
| 8I1A |
1.4 |
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 8.6 |
| 8I1C |
1.4 |
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGTP at pH 9.1 |
| 8I1D |
1.2 |
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 7.7 |
| 8I1E |
1.1 |
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.0 |
| 8I1F |
1.05 |
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 8.6 |
| 8I1G |
1.18 |
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 9.1 |
| 8I1H |
1.18 |
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dATP at pH 9.7 |
| 8I1I |
1.2 |
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 7.7 |
| 8I1J |
1.08 |
Crystal structure of human MTH1(G2K/D120N mutant) in complex with 2-oxo-dATP at pH 9.7 |
| 8I8S |
1.42 |
Crystal structure of human MTH1(G2K mutant) in complex with 8-oxo-dGMP and Mn2+ |
| 8I8T |
1.22 |
Crystal structure of human MTH1(G2K mutant) in complex with 2-oxo-dAMP and Mn2+ |
