Protein family
The protein has not catalytic activity
Protein sequence
Protein function
Publications
Catalytic activity
| PDB | Resolution (Å) | PDB name |
|---|
GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0007339 | binding of sperm to zona pellucida |
| Biological Process | GO:0097345 | mitochondrial outer membrane permeabilization |
| Biological Process | GO:0006820 | monoatomic anion transport |
| Biological Process | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway |
| Biological Process | GO:0032272 | negative regulation of protein polymerization |
| Molecular Function | GO:0097001 | ceramide binding |
| Molecular Function | GO:0015485 | cholesterol binding |
| Molecular Function | GO:0000166 | nucleotide binding |
| Molecular Function | GO:0031210 | phosphatidylcholine binding |
| Molecular Function | GO:0015288 | porin activity |
| Molecular Function | GO:0008308 | voltage-gated monoatomic anion channel activity |
| Cellular Component | GO:0001669 | acrosomal vesicle |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0045121 | membrane raft |
| Cellular Component | GO:0031966 | mitochondrial membrane |
| Cellular Component | GO:0042645 | mitochondrial nucleoid |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0046930 | pore complex |
| Cellular Component | GO:0097225 | sperm midpiece |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-5689880 | Ub-specific processing proteases | Leaf | R-HSA-392499 | Metabolism of proteins |
| R-HSA-8949215 | Mitochondrial calcium ion transport | Internal node | R-HSA-382551 | Transport of small molecules |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Membrane | ECO:0000269 | PubMed:27641616 |
| Mitochondrion outer membrane | ECO:0000269 | PubMed:31015432 |
| Mitochondrion outer membrane | ECO:0000269 | PubMed:7539795 |
| HPO ID
|
HPO name |
|---|
| Tissue
|
Cell type
|
Expression level | Reliability |
|---|---|---|---|
| adrenal gland | glandular cells | High | Enhanced |
| appendix | glandular cells | High | Enhanced |
| appendix | lymphoid tissue | Medium | Enhanced |
| breast | glandular cells | Medium | Enhanced |
| breast | myoepithelial cells | Medium | Enhanced |
| bronchus | respiratory epithelial cells | Medium | Enhanced |
| caudate | neuronal cells | Medium | Enhanced |
| cerebellum | Purkinje cells - cytoplasm/membrane | High | Enhanced |
| cerebellum | Purkinje cells - dendrites | High | Enhanced |
| cerebellum | processes in molecular layer | Medium | Enhanced |
| cerebellum | synaptic glomeruli - core | High | Enhanced |
| cerebellum | white matter cells - cytoplasm/membrane | High | Enhanced |
| cerebral cortex | endothelial cells | Low | Enhanced |
| cerebral cortex | glial cells | Medium | Enhanced |
| cerebral cortex | neuronal cells | Medium | Enhanced |
| cerebral cortex | neuropil | Medium | Enhanced |
| cervix | glandular cells | Medium | Enhanced |
| colon | endothelial cells | Low | Enhanced |
| colon | glandular cells | High | Enhanced |
| colon | peripheral nerve/ganglion | Medium | Enhanced |
| duodenum | glandular cells | High | Enhanced |
| endometrium 1 | glandular cells | High | Enhanced |
| endometrium 2 | glandular cells | Low | Enhanced |
| epididymis | glandular cells | Medium | Enhanced |
| esophagus | squamous epithelial cells | High | Enhanced |
| fallopian tube | glandular cells | Medium | Enhanced |
| gallbladder | glandular cells | High | Enhanced |
| heart muscle | cardiomyocytes | High | Enhanced |
| hippocampus | neuronal cells | High | Enhanced |
| kidney | cells in glomeruli | Medium | Enhanced |
| kidney | cells in tubules | High | Enhanced |
| liver | cholangiocytes | Medium | Enhanced |
| liver | hepatocytes | Low | Enhanced |
| lung | macrophages | Medium | Enhanced |
| nasopharynx | respiratory epithelial cells | High | Enhanced |
| oral mucosa | squamous epithelial cells | Medium | Enhanced |
| pancreas | exocrine glandular cells | Medium | Enhanced |
| pancreas | pancreatic endocrine cells | Medium | Enhanced |
| parathyroid gland | glandular cells | High | Enhanced |
| placenta | decidual cells | Medium | Enhanced |
| placenta | trophoblastic cells | High | Enhanced |
| prostate | glandular cells | Medium | Enhanced |
| rectum | glandular cells | High | Enhanced |
| salivary gland | glandular cells | High | Enhanced |
| seminal vesicle | glandular cells | High | Enhanced |
| skeletal muscle | myocytes | Medium | Enhanced |
| skin 1 | cells in basal layer | Medium | Enhanced |
| skin 1 | cells in granular layer | Medium | Enhanced |
| skin 1 | cells in spinous layer | Medium | Enhanced |
| skin 1 | eccrine glands | Medium | Enhanced |
| skin 1 | hair follicles | Medium | Enhanced |
| skin 1 | langerhans cells | Medium | Enhanced |
| skin 1 | melanocytes | Medium | Enhanced |
| skin 1 | sebaceous glands | Medium | Enhanced |
| skin 2 | cells in basal layer | Medium | Enhanced |
| skin 2 | cells in granular layer | Medium | Enhanced |
| skin 2 | cells in spinous layer | Medium | Enhanced |
| skin 2 | fibrohistiocytic cells | Medium | Enhanced |
| skin 2 | langerhans cells | Medium | Enhanced |
| skin 2 | melanocytes | Medium | Enhanced |
| small intestine | glandular cells | High | Enhanced |
| soft tissue 1 | peripheral nerve | Low | Enhanced |
| soft tissue 2 | peripheral nerve | Low | Enhanced |
| spleen | cells in red pulp | Low | Enhanced |
| spleen | cells in white pulp | Medium | Enhanced |
| stomach 1 | glandular cells | High | Enhanced |
| stomach 2 | glandular cells | High | Enhanced |
| testis | Leydig cells | High | Enhanced |
| testis | sertoli cells | Medium | Enhanced |
| thyroid gland | glandular cells | Medium | Enhanced |
| tonsil | germinal center cells | Low | Enhanced |
| tonsil | non-germinal center cells | Low | Enhanced |
| tonsil | squamous epithelial cells | Medium | Enhanced |
| urinary bladder | urothelial cells | High | Enhanced |
| vagina | squamous epithelial cells | Medium | Enhanced |
| Disease name | MONDO ID
|
ICD10
|
ICD10 chapter
|
OMIM
|
Orphanet
|
|---|