MultifacetedProtDB - Bologna Biocomputing Group

Catalytic activity

EC number	EC number description
1.14.14.-	Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor;
1.14.14.73	Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor; albendazole monooxygenase (sulfoxide-forming)
1.14.14.74	Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor; albendazole monooxygenase (hydroxylating)
5.4.4.7	Isomerases; Intramolecular transferases; Transferring hydroxy groups; hydroperoxy icosatetraenoate isomerase

Publications

GO ontology	GO term	GO description
Biological Process	GO:0019373	epoxygenase P450 pathway
Biological Process	GO:0006631	fatty acid metabolic process
Biological Process	GO:0006690	icosanoid metabolic process
Biological Process	GO:0043651	linoleic acid metabolic process
Biological Process	GO:0006082	organic acid metabolic process
Biological Process	GO:0008016	regulation of heart contraction
Biological Process	GO:0006805	xenobiotic metabolic process
Molecular Function	GO:0008405	arachidonic acid 11,12-epoxygenase activity
Molecular Function	GO:0008404	arachidonic acid 14,15-epoxygenase activity
Molecular Function	GO:0106301	arachidonic acid 5,6-epoxygenase activity
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity
Molecular Function	GO:0020037	heme binding
Molecular Function	GO:0106255	hydroperoxy icosatetraenoate isomerase activity
Molecular Function	GO:0005506	iron ion binding
Molecular Function	GO:0016853	isomerase activity
Molecular Function	GO:0071614	linoleic acid epoxygenase activity
Molecular Function	GO:0004497	monooxygenase activity
Molecular Function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0070062	extracellular exosome
Cellular Component	GO:0043231	intracellular membrane-bounded organelle

InterPro	InterPro name
IPR001128	Cytochrome P450
IPR002401	Cytochrome P450, E-class, group I
IPR008071	Cytochrome P450, E-class, group I, CYP2J-like
IPR017972	Cytochrome P450, conserved site
IPR036396	Cytochrome P450 superfamily

Reactome	Reactome Name	Node type	Reactome Root	Reactome Root Name
R-HSA-211935	Fatty acids	Leaf	R-HSA-1430728	Metabolism
R-HSA-211981	Xenobiotics	Internal node	R-HSA-1430728	Metabolism
R-HSA-2142670	Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	Leaf	R-HSA-1430728	Metabolism

Location	ECO term	Pubmed
Endoplasmic reticulum membrane
Microsome membrane	ECO:0000269	PubMed:8631948