| 2AGH |
|
Structural basis for cooperative transcription factor binding to the CBP coactivator |
| 2J2S |
|
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase |
| 2JYI |
|
Solution structure of MLL CXXC domain |
| 2KKF |
|
Solution structure of MLL CXXC domain in complex with palindromic CPG DNA |
| 2KU7 |
|
Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein |
| 2KYU |
|
The solution structure of the PHD3 finger of MLL |
| 2LXS |
|
Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core |
| 2LXT |
|
Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core |
| 2MSR |
|
Solution structure of LEDGF/p75 IBD in complex with MLL1 peptide (140-160) |
| 2MTN |
|
Solution structure of MLL-IBD complex |
| 2W5Y |
2.0 |
Binary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine. |
| 2W5Z |
2.2 |
Ternary Complex of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and histone peptide. |
| 3EG6 |
1.72 |
Structure of WDR5 bound to MLL1 peptide |
| 3EMH |
1.37 |
Structural basis of WDR5-MLL interaction |
| 3LQH |
1.72 |
Crystal structure of MLL1 PHD3-Bromo in the free form |
| 3LQI |
1.92 |
Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me2 peptide |
| 3LQJ |
1.9 |
Crystal structure of MLL1 PHD3-Bromo complexed with H3(1-9)K4me3 peptide |
| 3P4F |
2.35 |
Structural and biochemical insights into MLL1 core complex assembly and regulation. |
| 3U85 |
3.0 |
Crystal structure of human menin in complex with MLL1 |
| 3U88 |
3.0 |
Crystal structure of human menin in complex with MLL1 and LEDGF |
| 4ESG |
1.7 |
X-ray structure of WDR5-MLL1 Win motif peptide binary complex |
| 4GQ6 |
1.55 |
Human menin in complex with MLL peptide |
| 4NW3 |
2.82 |
Crystal structure of MLL CXXC domain in complex with a CpG DNA |
| 5F5E |
1.802 |
The Crystal Structure of MLL1 SET domain with N3816I/Q3867L mutation |
| 5F6L |
1.9 |
The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L |
| 5SVH |
2.05 |
Crystal structure of the KIX domain of CBP in complex with a MLL/c-Myb chimera |
| 6EMQ |
|
Solution structure of the LEDGF/p75 IBD - MLL1 (aa 111-160) complex |
| 6KIU |
3.2 |
Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom) |
| 6KIV |
4.0 |
Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) |
| 6KIX |
4.1 |
Cryo-EM structure of human MLL1-NCP complex, binding mode1 |
| 6KIZ |
4.5 |
Cryo-EM structure of human MLL1-NCP complex, binding mode2 |
| 6PWV |
6.2 |
Cryo-EM structure of MLL1 core complex bound to the nucleosome |
| 6PWW |
4.4 |
Cryo-EM structure of MLL1 in complex with RbBP5 and WDR5 bound to the nucleosome |
| 6U9K |
2.0 |
MLL1 SET N3861I/Q3867L bound to inhibitor 18 (TC-5153) |
| 6U9M |
2.05 |
MLL1 SET N3861I/Q3867L bound to inhibitor 16 (TC-5109) |
| 6U9N |
1.95 |
MLL1 SET N3861I/Q3867L bound to inhibitor 14 (TC-5139) |
| 6U9R |
2.1 |
MLL1 SET N3861I/Q3867L bound to inhibitor 12 (TC-5140) |
| 6W5I |
6.9 |
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class01) |
| 6W5M |
4.6 |
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class02) |
| 6W5N |
6.0 |
Cryo-EM structure of MLL1 in complex with RbBP5, WDR5, SET1, and ASH2L bound to the nucleosome (Class05) |
| 7MBM |
|
Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode01 |
| 7MBN |
|
Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode02 |
| 7RZD |
1.82 |
CRYSTAL STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PEPTIDE |
| 7RZJ |
1.8 |
CRYSTAL STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE |
| 7S79 |
1.53 |
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH SYNTHETIC PHOSPHONO-MLL PEPTIDE ANALOG |
| 7S7D |
1.56 |
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH SYNTHETIC SULFO-MLL PEPTIDE ANALOG |
| 7S8A |
2.1 |
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE, CUBIC CRYSTAL FORM |
| 7S8E |
1.6 |
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE AND BOUND GLYCEROL |
| 7S8F |
1.8 |
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PEPTIDE AND BOUND GLYCEROL |
| 7W67 |
2.194 |
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me0 peptide |
| 7W6A |
2.21 |
Crystal structure of the MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L complex |
| 7W6I |
2.56 |
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me1 peptide |
| 7W6J |
2.68 |
The crystal structure of MLL1 (N3861I/Q3867L/C3882SS)-RBBP5-ASH2L in complex with H3K4me2 peptide |
| 7ZEY |
|
Complex Cyp33-RRM : MLL1-PHD3 |
| 7ZEZ |
|
Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 |
