| 1K04 |
1.95 |
Crystal Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase |
| 1K05 |
2.9 |
Crystal structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase |
| 1MP8 |
1.6 |
Crystal structure of Focal Adhesion Kinase (FAK) |
| 1OW6 |
2.35 |
Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase |
| 1OW7 |
2.6 |
Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase |
| 1OW8 |
2.85 |
Paxillin LD2 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase |
| 2ETM |
2.3 |
Crystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative |
| 2IJM |
2.187 |
Crystal Structure of Focal Adhesion Kinase Domain with 2 molecules in the Asymmetric Unit Complexed with ADP and ATP |
| 3B71 |
2.82 |
CD4 endocytosis motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase |
| 3BZ3 |
2.2 |
Crystal Structure Analysis of Focal Adhesion Kinase with a Methanesulfonamide Diaminopyrimidine Inhibitor |
| 3PXK |
1.79 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH Pyrrolo[2,3-d]thiazole |
| 3S9O |
2.6 |
The Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase showing N-terminal interactions in cis |
| 4EBV |
1.67 |
Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor |
| 4EBW |
2.65 |
Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor |
| 4GU6 |
1.95 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-{3-[(5-Cyano-2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-ylamino)- methyl]-pyridin-2-yl}-N-methyl-methanesulfonamide |
| 4GU9 |
2.4 |
Focal adhesion kinase catalytic domain in complex with (2-Fluoro-phenyl)-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine |
| 4I4E |
1.55 |
Structure of Focal Adhesion Kinase catalytic domain in complex with hinge binding pyrazolobenzothiazine compound. |
| 4I4F |
1.75 |
Structure of Focal Adhesion Kinase catalytic domain in complex with an allosteric binding pyrazolobenzothiazine compound. |
| 4K8A |
2.91 |
Fragment-based discovery of Focal Adhesion Kinase Inhibitors |
| 4K9Y |
2.0 |
FOCAL ADHESION KINASE Catalytic domain in complex with 1-[4-(6-Amino-purin-9-yl)-phenyl]-3-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-urea |
| 4KAB |
2.71 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 3-Methyl-1,4-dihydro-pyrazolo[4,5-c]pyrazole |
| 4KAO |
2.39 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-(4-pyridin-3- yl-phenyl)-urea |
| 4NY0 |
2.8 |
Crystal structure of FERM domain of human focal adhesion kinase |
| 4Q9S |
2.07 |
Crystal Structure of human Focal Adhesion Kinase (Fak) bound to Compound1 (3,5-DIHYDRO[1,2,4]TRIAZINO[3,4-C][1,4]BENZOXAZIN-2(1H)-ONE) |
| 6I8Z |
1.99 |
Crystal structure of PTK2 in complex with BI-4464. |
| 6LES |
2.004 |
3D domain-swapped dimer of the maltose-binding protein fused to a fragment of the focal adhesion kinase |
| 6PW8 |
1.95 |
Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK) |
| 6YOJ |
1.361 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one |
| 6YQ1 |
1.784 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(3-{[2-(2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-methyl}-pyridin-2-yl)-methanesulfonamide |
| 6YR9 |
1.925 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(2-{[2-(2-oxo-2,3-dihydro-1H-indol-5-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-methyl}-phenyl)-methanesulfonamide |
| 6YT6 |
1.537 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(3-{[2-(2-oxo-2,3-dihydro-1H-indol-5-ylamino)-pyrimidin-4-ylamino]-methyl}-pyridin-2-yl)-methanesulfonamide |
| 6YVS |
1.81 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 5-{4-[(Pyridin-3-ylmethyl)-amino]-5-trifluoromethyl-pyrimidin-2-ylamino}-1,3-dihydro-indol-2-one |
| 6YVY |
1.918 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH 4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide |
| 6YXV |
2.298 |
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-{3-[(2-phenylamino-5-trifluoromethyl-pyrimidin-4-ylamino)-methyl]-pyridin-2-yl}-methanesulfonamide |
| 7PI4 |
2.24 |
FAK Protac GSK215 in complex with FAK and pVHL:ElonginC:ElonginB |
| 7W7Z |
2.15 |
Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase |
| 7W8I |
1.943 |
Crystal structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase |
| 7W9U |
2.163 |
Crystal Structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase |
