MultifacetedProtDB - Bologna Biocomputing Group

EC number	EC number description
2.4.3.2	Transferases; Glycosyltransferases; Sialyltransferases; β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminide α-2,3-sialyltransferase
2.4.3.4	Transferases; Glycosyltransferases; Sialyltransferases; β-galactoside α-2,3-sialyltransferase
2.4.3.6	Transferases; Glycosyltransferases; Sialyltransferases; N-acetyllactosaminide α-2,3-sialyltransferase

GO ontology	GO term	GO description
Biological Process	GO:0016266	O-glycan processing
Biological Process	GO:0050890	cognition
Biological Process	GO:0009247	glycolipid biosynthetic process
Biological Process	GO:0009101	glycoprotein biosynthetic process
Biological Process	GO:0018146	keratan sulfate biosynthetic process
Biological Process	GO:0030259	lipid glycosylation
Biological Process	GO:0009312	oligosaccharide biosynthetic process
Biological Process	GO:0030194	positive regulation of blood coagulation
Biological Process	GO:1903238	positive regulation of leukocyte tethering or rolling
Biological Process	GO:0006486	protein glycosylation
Biological Process	GO:1990743	protein sialylation
Biological Process	GO:0097503	sialylation
Biological Process	GO:0019082	viral protein processing
Molecular Function	GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity
Molecular Function	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
Molecular Function	GO:0047288	monosialoganglioside sialyltransferase activity
Molecular Function	GO:0004513	neolactotetraosylceramide alpha-2,3-sialyltransferase activity
Molecular Function	GO:0008373	sialyltransferase activity
Cellular Component	GO:0032580	Golgi cisterna membrane
Cellular Component	GO:0000139	Golgi membrane
Cellular Component	GO:0005576	extracellular region
Cellular Component	GO:0016020	membrane

InterPro	InterPro name
IPR001675	Glycosyl transferase family 29
IPR012163	Sialyltransferase
IPR038578	GT29-like superfamiliy

Pfam	Pfam name
PF00777	Glycosyltransferase family 29 (sialyltransferase)

Reactome	Reactome Name	Node type	Reactome Root	Reactome Root Name
R-HSA-1912420	Pre-NOTCH Processing in Golgi	Leaf	R-HSA-162582	Signal Transduction
R-HSA-2022854	Keratan sulfate biosynthesis	Leaf	R-HSA-1430728	Metabolism
R-HSA-4085001	Sialic acid metabolism	Leaf	R-HSA-392499	Metabolism of proteins
R-HSA-9037629	Lewis blood group biosynthesis	Leaf	R-HSA-1430728	Metabolism
R-HSA-9683673	Maturation of protein 3a	Leaf	R-HSA-1643685	Disease
R-HSA-9694548	Maturation of spike protein	Leaf	R-HSA-1643685	Disease
R-HSA-9694719	Maturation of protein 3a	Leaf	R-HSA-1643685	Disease
R-HSA-975577	N-Glycan antennae elongation	Leaf	R-HSA-392499	Metabolism of proteins
R-HSA-977068	Termination of O-glycan biosynthesis	Leaf	R-HSA-392499	Metabolism of proteins

Tissue	Cell type	Expression level	Reliability
adrenal gland	glandular cells	Medium	Approved
appendix	glandular cells	Low	Approved
bone marrow	hematopoietic cells	High	Approved
breast	glandular cells	Low	Approved
breast	myoepithelial cells	Low	Approved
bronchus	respiratory epithelial cells	Low	Approved
caudate	neuronal cells	Low	Approved
colon	glandular cells	Low	Approved
duodenum	glandular cells	Medium	Approved
endometrium 2	glandular cells	Low	Approved
epididymis	glandular cells	Low	Approved
esophagus	squamous epithelial cells	Medium	Approved
gallbladder	glandular cells	Medium	Approved
kidney	cells in tubules	Low	Approved
ovary	follicle cells	Medium	Approved
prostate	glandular cells	Low	Approved
rectum	glandular cells	Low	Approved
salivary gland	glandular cells	Low	Approved
small intestine	glandular cells	Low	Approved
spleen	cells in red pulp	Medium	Approved
spleen	cells in white pulp	Low	Approved
stomach 1	glandular cells	Low	Approved
stomach 2	glandular cells	Medium	Approved
testis	Leydig cells	Medium	Approved
testis	cells in seminiferous ducts	High	Approved
thyroid gland	glandular cells	Medium	Approved
tonsil	germinal center cells	Low	Approved
tonsil	non-germinal center cells	Medium	Approved
urinary bladder	urothelial cells	Medium	Approved

Location	ECO term	Pubmed
Golgi apparatus, Golgi stack membrane
Secreted