MultifacetedProtDB - Bologna Biocomputing Group

Catalytic activity

EC number	EC number description
3.1.3.48	Hydrolases; Acting on ester bonds; Phosphoric-monoester hydrolases; protein-tyrosine-phosphatase
3.1.3.64	Hydrolases; Acting on ester bonds; Phosphoric-monoester hydrolases; phosphatidylinositol-3-phosphatase
3.1.3.95	Hydrolases; Acting on ester bonds; Phosphoric-monoester hydrolases; phosphatidylinositol-3,5-bisphosphate 3-phosphatase

Publications

GO ontology	GO term	GO description
Biological Process	GO:0042149	cellular response to glucose starvation
Biological Process	GO:0016236	macroautophagy
Biological Process	GO:1904562	phosphatidylinositol 5-phosphate metabolic process
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation
Biological Process	GO:0006470	protein dephosphorylation
Biological Process	GO:2000785	regulation of autophagosome assembly
Biological Process	GO:0010506	regulation of autophagy
Biological Process	GO:0060304	regulation of phosphatidylinositol dephosphorylation
Molecular Function	GO:0046872	metal ion binding
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Molecular Function	GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity
Molecular Function	GO:0019903	protein phosphatase binding
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity
Molecular Function	GO:0004725	protein tyrosine phosphatase activity
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0019898	extrinsic component of membrane
Cellular Component	GO:0016020	membrane

InterPro	InterPro name
IPR000306	FYVE zinc finger
IPR003595	Protein-tyrosine phosphatase, catalytic
IPR010569	Myotubularin-like, phosphatase domain
IPR011011	Zinc finger, FYVE/PHD-type
IPR013083	Zinc finger, RING/FYVE/PHD-type
IPR016130	Protein-tyrosine phosphatase, active site
IPR017455	Zinc finger, FYVE-related
IPR029021	Protein-tyrosine phosphatase-like
IPR030564	Myotubularin family
IPR035888	Myotubularin-related protein 3, PH-GRAM domain
IPR046352	Myotubularin-related protein 3, protein tyrosine phosphatase domain

Pfam	Pfam name
PF01363	FYVE zinc finger
PF06602	Myotubularin-like phosphatase domain

Reactome	Reactome Name	Node type	Reactome Root	Reactome Root Name
R-HSA-1632852	Macroautophagy	Internal node	R-HSA-9612973	Autophagy
R-HSA-1660499	Synthesis of PIPs at the plasma membrane	Leaf	R-HSA-1430728	Metabolism

Location	ECO term	Pubmed
Cytoplasm	ECO:0000269	PubMed:11676921
Membrane	ECO:0000269	PubMed:11676921