Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
1.3.1.48
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor;
13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor;
2-alkenal reductase [NAD(P)+]
GO ontology | GO term | GO description |
---|---|---|
Biological Process | GO:0036102 | leukotriene B4 metabolic process |
Biological Process | GO:0006691 | leukotriene metabolic process |
Biological Process | GO:2001302 | lipoxin A4 metabolic process |
Biological Process | GO:0006693 | prostaglandin metabolic process |
Biological Process | GO:0097327 | response to antineoplastic agent |
Molecular Function | GO:0036185 | 13-lipoxin reductase activity |
Molecular Function | GO:0036132 | 13-prostaglandin reductase activity |
Molecular Function | GO:0047522 | 15-oxoprostaglandin 13-oxidase activity |
Molecular Function | GO:0035798 | 2-alkenal reductase (NADP+) activity |
Molecular Function | GO:0097257 | leukotriene B4 12-hydroxy dehydrogenase activity |
Cellular Component | GO:0005737 | cytoplasm |
Cellular Component | GO:0070062 | extracellular exosome |
InterPro | InterPro name |
---|---|
IPR011032 | GroES-like superfamily |
IPR013149 | Alcohol dehydrogenase-like, C-terminal |
IPR014190 | Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase |
IPR020843 | Polyketide synthase, enoylreductase domain |
IPR036291 | NAD(P)-binding domain superfamily |
IPR041694 | Oxidoreductase, N-terminal domain |
IPR045010 | Medium-chain dehydrogenase/reductase |
Pfam | Pfam name |
---|---|
PF00107 | Zinc-binding dehydrogenase |
PF16884 | N-terminal domain of oxidoreductase |
Reactome | Reactome Name | Node type | Reactome Root | Reactome Root Name |
---|---|---|---|---|
R-HSA-2142691 | Synthesis of Leukotrienes (LT) and Eoxins (EX) | Leaf | R-HSA-1430728 | Metabolism |
R-HSA-2142700 | Synthesis of Lipoxins (LX) | Leaf | R-HSA-1430728 | Metabolism |
Location | ECO term | Pubmed |
---|---|---|
Cytoplasm | ECO:0000250 |