Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
1.3.1.48
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor;
13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor;
2-alkenal reductase [NAD(P)+]
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0036102 | leukotriene B4 metabolic process |
| Biological Process | GO:0006691 | leukotriene metabolic process |
| Biological Process | GO:2001302 | lipoxin A4 metabolic process |
| Biological Process | GO:0006693 | prostaglandin metabolic process |
| Biological Process | GO:0097327 | response to antineoplastic agent |
| Molecular Function | GO:0036185 | 13-lipoxin reductase activity |
| Molecular Function | GO:0036132 | 13-prostaglandin reductase activity |
| Molecular Function | GO:0047522 | 15-oxoprostaglandin 13-oxidase activity |
| Molecular Function | GO:0035798 | 2-alkenal reductase (NADP+) activity |
| Molecular Function | GO:0097257 | leukotriene B4 12-hydroxy dehydrogenase activity |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0070062 | extracellular exosome |
| InterPro
|
InterPro name |
|---|---|
| IPR011032 | GroES-like superfamily |
| IPR013149 | Alcohol dehydrogenase-like, C-terminal |
| IPR014190 | Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase |
| IPR020843 | Polyketide synthase, enoylreductase domain |
| IPR036291 | NAD(P)-binding domain superfamily |
| IPR041694 | Oxidoreductase, N-terminal domain |
| IPR045010 | Medium-chain dehydrogenase/reductase |
| Pfam
|
Pfam name |
|---|---|
| PF00107 | Zinc-binding dehydrogenase |
| PF16884 | N-terminal domain of oxidoreductase |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-2142691 | Synthesis of Leukotrienes (LT) and Eoxins (EX) | Leaf | R-HSA-1430728 | Metabolism |
| R-HSA-2142700 | Synthesis of Lipoxins (LX) | Leaf | R-HSA-1430728 | Metabolism |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Cytoplasm | ECO:0000250 |