Protein family
The protein has not catalytic activity
Protein sequence
Protein function
Catalytic activity
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 5Z56 | 5.1 | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. |
| 5Z57 | 6.5 | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom |
| 5Z58 | 4.9 | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. |
| 6AH0 | 5.7 | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) |
| 6AHD | 3.8 | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution |
| 6FF4 | 3.4 | human Bact spliceosome core structure |
| 6FF7 | 4.5 | human Bact spliceosome core structure |
| 6QX9 | 3.28 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). |
| 6Y53 | 7.1 | human 17S U2 snRNP low resolution part |
| 6Y5Q | 7.1 | human 17S U2 snRNP |
| 7ABG | 7.8 | Human pre-Bact-1 spliceosome |
| 7ABH | 4.5 | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) |
| 7ABI | 8.0 | Human pre-Bact-2 spliceosome |
| 7EVO | 2.5 | The cryo-EM structure of the human 17S U2 snRNP |
| 7ONB | 3.1 | Structure of the U2 5' module of the A3'-SSA complex |
| 7Q4O | 2.1 | Substrate-bound A-like U2 snRNP |
| 7Q4P | 2.15 | U2 snRNP after ATP-dependent remodelling |
| 8HK1 | 2.7 | The cryo-EM structure of human pre-17S U2 snRNP |
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:1903241 | U2-type prespliceosome assembly |
| Biological Process | GO:0000389 | mRNA 3'-splice site recognition |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0010976 | positive regulation of neuron projection development |
| Biological Process | GO:0000245 | spliceosomal complex assembly |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Cellular Component | GO:0005686 | U2 snRNP |
| Cellular Component | GO:0071005 | U2-type precatalytic spliceosome |
| Cellular Component | GO:0071004 | U2-type prespliceosome |
| Cellular Component | GO:0005684 | U2-type spliceosomal complex |
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-72163 | mRNA Splicing - Major Pathway | Leaf | R-HSA-8953854 | Metabolism of RNA |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Nucleus | ECO:0000255 | PubMed:10882114 |
| Nucleus | ECO:0000255 | PubMed:21349847 |
| Nucleus | ECO:0000255 | PubMed:29360106 |
| Nucleus | ECO:0000255 | PubMed:29361316 |
| Nucleus | ECO:0000255 | PubMed:30315277 |