MultifacetedProtDB - Bologna Biocomputing Group

Catalytic activity

EC number	EC number description
3.6.1.13	Hydrolases; Acting on acid anhydrides; In phosphorus-containing anhydrides; ADP-ribose diphosphatase
3.6.1.16	Hydrolases; Acting on acid anhydrides; In phosphorus-containing anhydrides; CDP-glycerol diphosphatase
3.6.1.53	Hydrolases; Acting on acid anhydrides; In phosphorus-containing anhydrides; Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase

Publications

GO ontology	GO term	GO description
Molecular Function	GO:0008663	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity
Molecular Function	GO:0047631	ADP-ribose diphosphatase activity
Molecular Function	GO:0047734	CDP-glycerol diphosphatase activity
Molecular Function	GO:0030145	manganese ion binding
Cellular Component	GO:0005829	cytosol

InterPro	InterPro name
IPR004843	Calcineurin-like phosphoesterase domain, ApaH type
IPR029052	Metallo-dependent phosphatase-like
IPR041869	Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase

Pfam	Pfam name
PF00149	Calcineurin-like phosphoesterase

Reactome	Reactome Name	Node type	Reactome Root	Reactome Root Name
R-HSA-2393930	Phosphate bond hydrolysis by NUDT proteins	Leaf	R-HSA-1430728	Metabolism

Tissue	Cell type	Expression level	Reliability
adrenal gland	glandular cells	Low	Approved
appendix	glandular cells	Medium	Approved
bone marrow	hematopoietic cells	Low	Approved
bronchus	respiratory epithelial cells	Low	Approved
caudate	neuronal cells	Low	Approved
cerebellum	Purkinje cells	Medium	Approved
cerebellum	cells in molecular layer	Low	Approved
cerebral cortex	neuronal cells	Medium	Approved
cerebral cortex	neuropil	Low	Approved
colon	glandular cells	Low	Approved
duodenum	glandular cells	Medium	Approved
endometrium 1	glandular cells	Low	Approved
endometrium 2	glandular cells	Medium	Approved
epididymis	glandular cells	Low	Approved
gallbladder	glandular cells	Low	Approved
heart muscle	cardiomyocytes	Low	Approved
hippocampus	neuronal cells	Low	Approved
kidney	cells in tubules	Low	Approved
lung	macrophages	Low	Approved
lymph node	non-germinal center cells	Low	Approved
pancreas	exocrine glandular cells	Low	Approved
parathyroid gland	glandular cells	Low	Approved
placenta	trophoblastic cells	Low	Approved
prostate	glandular cells	Low	Approved
rectum	glandular cells	Medium	Approved
skin 1	Langerhans	Low	Approved
skin 2	epidermal cells	Low	Approved
small intestine	glandular cells	Medium	Approved
spleen	cells in red pulp	Low	Approved
stomach 1	glandular cells	Low	Approved
stomach 2	glandular cells	Medium	Approved
testis	Leydig cells	High	Approved
testis	sertoli cells	Low	Approved
testis	spermatogonia cells	High	Approved
thyroid gland	glandular cells	High	Approved
tonsil	non-germinal center cells	Low	Approved
tonsil	squamous epithelial cells	Low	Approved