MultifacetedProtDB - Bologna Biocomputing Group

Summary of Q5BJF6

Gene: ODF2
Protein: Outer dense fiber protein 2

Protein family
Protein sequence
Protein function

Catalytic activity

The protein has not catalytic activity

Publications

Structure

GO term

GO ontology	GO term	GO description
Biological Process	GO:0030154	cell differentiation
Biological Process	GO:0010457	centriole-centriole cohesion
Biological Process	GO:0044782	cilium organization
Biological Process	GO:0008104	protein localization
Biological Process	GO:1902017	regulation of cilium assembly
Biological Process	GO:0007283	spermatogenesis
Molecular Function	GO:0031267	small GTPase binding
Molecular Function	GO:0005198	structural molecule activity
Cellular Component	GO:0120103	centriolar subdistal appendage
Cellular Component	GO:0005814	centriole
Cellular Component	GO:0005813	centrosome
Cellular Component	GO:0036064	ciliary basal body
Cellular Component	GO:0005929	cilium
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0043231	intracellular membrane-bounded organelle
Cellular Component	GO:0005874	microtubule
Cellular Component	GO:0005634	nucleus
Cellular Component	GO:0036126	sperm flagellum
Cellular Component	GO:0000922	spindle pole

InterPro / Pfam

Reactome

Reactome	Reactome Name	Node type	Reactome Root	Reactome Root Name
R-HSA-2565942	Regulation of PLK1 Activity at G2/M Transition	Leaf	R-HSA-1640170	Cell Cycle
R-HSA-380259	Loss of Nlp from mitotic centrosomes	Leaf	R-HSA-1640170	Cell Cycle
R-HSA-380270	Recruitment of mitotic centrosome proteins and complexes	Leaf	R-HSA-1640170	Cell Cycle
R-HSA-380284	Loss of proteins required for interphase microtubule organization from the centrosome	Internal node	R-HSA-1640170	Cell Cycle
R-HSA-380320	Recruitment of NuMA to mitotic centrosomes	Leaf	R-HSA-1640170	Cell Cycle
R-HSA-5620912	Anchoring of the basal body to the plasma membrane	Leaf	R-HSA-1852241	Organelle biogenesis and maintenance
R-HSA-8854518	AURKA Activation by TPX2	Leaf	R-HSA-1640170	Cell Cycle

Subcellular location

Interactor | Variant | Drug

Phenotype

Tissue and cell type

Tissue	Cell type	Expression level	Reliability
bronchus	ciliated cells (cilia axoneme)	High	Enhanced
bronchus	ciliated cells (tip of cilia)	High	Enhanced
fallopian tube	ciliated cells (cilia axoneme)	High	Enhanced
fallopian tube	ciliated cells (tip of cilia)	High	Enhanced
lung	macrophages	Medium	Enhanced
nasopharynx	ciliated cells (cilia axoneme)	High	Enhanced
nasopharynx	ciliated cells (tip of cilia)	High	Enhanced
testis	elongated or late spermatids	High	Enhanced
testis	pachytene spermatocytes	Low	Enhanced
testis	preleptotene spermatocytes	Low	Enhanced
testis	round or early spermatids	Medium	Enhanced
testis	spermatogonia cells	Low	Enhanced

Disease