Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
2.3.1.-
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups;
2.3.1.225
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups;
protein S-acyltransferase
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 6BML | 2.95 | Structure of human DHHC20 palmitoyltransferase, irreversibly inhibited by 2-bromopalmitate |
| 6BMM | 2.35 | Structure of human DHHC20 palmitoyltransferase, space group P21 |
| 6BMN | 2.25 | Structure of human DHHC20 palmitoyltransferase, space group P63 |
| 7KHM | 2.88 | Crystal structure of hDHHS20 bound to palmitoyl CoA |
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0018230 | peptidyl-L-cysteine S-palmitoylation |
| Biological Process | GO:0044794 | positive regulation by host of viral process |
| Biological Process | GO:0018345 | protein palmitoylation |
| Biological Process | GO:0006612 | protein targeting to membrane |
| Biological Process | GO:0016188 | synaptic vesicle maturation |
| Molecular Function | GO:0016409 | palmitoyltransferase activity |
| Molecular Function | GO:0019705 | protein-cysteine S-myristoyltransferase activity |
| Molecular Function | GO:0019706 | protein-cysteine S-palmitoyltransferase activity |
| Molecular Function | GO:0140439 | protein-cysteine S-stearoyltransferase activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane |
| Cellular Component | GO:0043231 | intracellular membrane-bounded organelle |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-9694548 | Maturation of spike protein | Leaf | R-HSA-1643685 | Disease |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Cell membrane | ECO:0000269 | PubMed:27153536 |
| Cell membrane | ECO:0000269 | PubMed:29326245 |
| Cytoplasm, perinuclear region | ECO:0000269 | PubMed:27153536 |
| Endoplasmic reticulum membrane | ECO:0000305 | PubMed:34599882 |
| Endoplasmic reticulum-Golgi intermediate compartment membrane | ECO:0000305 | PubMed:34599882 |
| Golgi apparatus membrane | ECO:0000269 | PubMed:29326245 |