Protein family
Protein sequence
Protein function
Publications
Catalytic activity
EC number
EC number description
3.1.1.-
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases;
3.1.1.71
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases;
acetylalkylglycerol acetylhydrolase
| PDB | Resolution (Å) | PDB name |
|---|
GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0060395 | SMAD protein signal transduction |
| Biological Process | GO:0046485 | ether lipid metabolic process |
| Biological Process | GO:0016042 | lipid catabolic process |
| Biological Process | GO:0034383 | low-density lipoprotein particle clearance |
| Biological Process | GO:0006470 | protein dephosphorylation |
| Biological Process | GO:0006805 | xenobiotic metabolic process |
| Molecular Function | GO:0047378 | acetylalkylglycerol acetylhydrolase activity |
| Molecular Function | GO:0042301 | phosphate ion binding |
| Molecular Function | GO:0017171 | serine hydrolase activity |
| Molecular Function | GO:0004771 | sterol esterase activity |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-8964038 | LDL clearance | Leaf | R-HSA-382551 | Transport of small molecules |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Cell membrane | ECO:0000305 | PubMed:12149457 |
| Cell membrane | ECO:0000305 | PubMed:17052608 |
| Microsome | ECO:0000250 |
| HPO ID
|
HPO name |
|---|
| Tissue
|
Cell type
|
Expression level | Reliability |
|---|---|---|---|
| adipose tissue | adipocytes | Low | Enhanced |
| adrenal gland | glandular cells | Medium | Enhanced |
| appendix | glandular cells | Medium | Enhanced |
| appendix | lymphoid tissue | Medium | Enhanced |
| breast | glandular cells | Low | Enhanced |
| bronchus | respiratory epithelial cells | Low | Enhanced |
| caudate | neuronal cells | High | Enhanced |
| cerebellum | GLUC cells - cytoplasm/membrane | Medium | Enhanced |
| cerebellum | Purkinje cells - cytoplasm/membrane | Medium | Enhanced |
| cerebellum | Purkinje cells - dendrites | Medium | Enhanced |
| cerebellum | molecular layer cells - cytoplasm/membrane | Medium | Enhanced |
| cerebral cortex | glial cells | Medium | Enhanced |
| cerebral cortex | neuronal cells | High | Enhanced |
| cerebral cortex | neuropil | Low | Enhanced |
| colon | glandular cells | Medium | Enhanced |
| colon | peripheral nerve/ganglion | Low | Enhanced |
| duodenum | glandular cells | High | Enhanced |
| endometrium 1 | glandular cells | Low | Enhanced |
| endometrium 2 | glandular cells | Low | Enhanced |
| gallbladder | glandular cells | Low | Enhanced |
| heart muscle | cardiomyocytes | Medium | Enhanced |
| hippocampus | neuronal cells | High | Enhanced |
| kidney | collecting ducts | Low | Enhanced |
| kidney | distal tubules | Low | Enhanced |
| kidney | proximal tubules (cell body) | Low | Enhanced |
| lung | macrophages | Medium | Enhanced |
| lymph node | non-germinal center cells | Medium | Enhanced |
| nasopharynx | respiratory epithelial cells | Low | Enhanced |
| pancreas | exocrine glandular cells | Low | Enhanced |
| placenta | cytotrophoblasts | High | Enhanced |
| placenta | decidual cells | Medium | Enhanced |
| placenta | endothelial cells | Medium | Enhanced |
| placenta | hofbauer cells | Medium | Enhanced |
| placenta | syncytiotrophoblasts - cell body | High | Enhanced |
| placenta | syncytiotrophoblasts - microvilli | Medium | Enhanced |
| prostate | glandular cells | Low | Enhanced |
| rectum | glandular cells | Medium | Enhanced |
| salivary gland | glandular cells | Low | Enhanced |
| skin 2 | epidermal cells | Low | Enhanced |
| small intestine | glandular cells | Low | Enhanced |
| smooth muscle | smooth muscle cells | Low | Enhanced |
| stomach 1 | glandular cells | Medium | Enhanced |
| stomach 2 | glandular cells | Medium | Enhanced |
| testis | Leydig cells | Medium | Enhanced |
| testis | elongated or late spermatids | Medium | Enhanced |
| testis | pachytene spermatocytes | Low | Enhanced |
| testis | preleptotene spermatocytes | Medium | Enhanced |
| testis | round or early spermatids | Low | Enhanced |
| testis | spermatogonia cells | High | Enhanced |
| thyroid gland | glandular cells | Low | Enhanced |
| tonsil | germinal center cells | Medium | Enhanced |
| tonsil | squamous epithelial cells | Medium | Enhanced |
| Disease name | MONDO ID
|
ICD10
|
ICD10 chapter
|
OMIM
|
Orphanet
|
|---|