Protein family
Protein sequence
Protein function
Publications
Catalytic activity
EC number
EC number description
2.3.1.-
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups;
2.3.1.225
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups;
protein S-acyltransferase
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 3EU9 | 1.99 | The ankyrin repeat domain of Huntingtin interacting protein 14 |
| 5W7I | 2.105 | X-ray structure of ankyrin repeat domain of DHHC17 in complex with Snap25b peptide |
| 5W7J | 2.202 | X-ray structure of the E89A variant of ankyrin repeat domain of DHHC17 in complex with Snap25b peptide |
GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0007409 | axonogenesis |
| Biological Process | GO:0042953 | lipoprotein transport |
| Biological Process | GO:0018230 | peptidyl-L-cysteine S-palmitoylation |
| Biological Process | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB signaling |
| Biological Process | GO:0018345 | protein palmitoylation |
| Biological Process | GO:0070372 | regulation of ERK1 and ERK2 cascade |
| Biological Process | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway |
| Biological Process | GO:0043067 | regulation of programmed cell death |
| Molecular Function | GO:0004869 | cysteine-type endopeptidase inhibitor activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0016409 | palmitoyltransferase activity |
| Molecular Function | GO:0019705 | protein-cysteine S-myristoyltransferase activity |
| Molecular Function | GO:0019706 | protein-cysteine S-palmitoyltransferase activity |
| Molecular Function | GO:0140439 | protein-cysteine S-stearoyltransferase activity |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0030660 | Golgi-associated vesicle membrane |
| Cellular Component | GO:0042995 | cell projection |
| Cellular Component | GO:0043231 | intracellular membrane-bounded organelle |
| Cellular Component | GO:0042734 | presynaptic membrane |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Cytoplasmic vesicle membrane | ECO:0000269 | PubMed:18794299 |
| Golgi apparatus membrane | ECO:0000269 | PubMed:15603740 |
| Golgi apparatus membrane | ECO:0000269 | PubMed:18794299 |
| Presynaptic cell membrane | ECO:0000269 | PubMed:18032660 |
| HPO ID
|
HPO name |
|---|
| Tissue
|
Cell type
|
Expression level | Reliability |
|---|---|---|---|
| adipose tissue | adipocytes | Medium | Approved |
| adrenal gland | glandular cells | Medium | Approved |
| appendix | glandular cells | Medium | Approved |
| appendix | lymphoid tissue | Low | Approved |
| bone marrow | hematopoietic cells | Medium | Approved |
| breast | glandular cells | Medium | Approved |
| breast | myoepithelial cells | Medium | Approved |
| caudate | glial cells | Medium | Approved |
| caudate | neuronal cells | Medium | Approved |
| cerebellum | Purkinje cells | Low | Approved |
| cerebellum | cells in granular layer | Medium | Approved |
| cerebellum | cells in molecular layer | Medium | Approved |
| cerebral cortex | endothelial cells | Low | Approved |
| cerebral cortex | glial cells | High | Approved |
| cerebral cortex | neuronal cells | High | Approved |
| cerebral cortex | neuropil | Low | Approved |
| colon | endothelial cells | Low | Approved |
| colon | glandular cells | Medium | Approved |
| colon | peripheral nerve/ganglion | Low | Approved |
| duodenum | glandular cells | Low | Approved |
| endometrium 1 | cells in endometrial stroma | Medium | Approved |
| endometrium 1 | glandular cells | High | Approved |
| endometrium 2 | cells in endometrial stroma | Medium | Approved |
| endometrium 2 | glandular cells | High | Approved |
| epididymis | glandular cells | Medium | Approved |
| fallopian tube | glandular cells | Low | Approved |
| hippocampus | glial cells | Medium | Approved |
| hippocampus | neuronal cells | High | Approved |
| kidney | cells in glomeruli | Low | Approved |
| kidney | cells in tubules | Low | Approved |
| liver | cholangiocytes | Low | Approved |
| lung | alveolar cells | Medium | Approved |
| lung | macrophages | Low | Approved |
| lymph node | germinal center cells | Low | Approved |
| lymph node | non-germinal center cells | Low | Approved |
| nasopharynx | respiratory epithelial cells | Low | Approved |
| pancreas | exocrine glandular cells | Low | Approved |
| pancreas | pancreatic endocrine cells | Low | Approved |
| placenta | decidual cells | High | Approved |
| placenta | trophoblastic cells | High | Approved |
| prostate | glandular cells | Medium | Approved |
| rectum | glandular cells | Low | Approved |
| salivary gland | glandular cells | Medium | Approved |
| seminal vesicle | glandular cells | High | Approved |
| skin 1 | fibroblasts | Medium | Approved |
| skin 2 | epidermal cells | Low | Approved |
| small intestine | glandular cells | Low | Approved |
| soft tissue 1 | fibroblasts | High | Approved |
| soft tissue 1 | peripheral nerve | Medium | Approved |
| soft tissue 2 | fibroblasts | High | Approved |
| spleen | cells in red pulp | Medium | Approved |
| stomach 2 | glandular cells | Low | Approved |
| testis | Leydig cells | Medium | Approved |
| testis | cells in seminiferous ducts | Medium | Approved |
| thyroid gland | glandular cells | Medium | Approved |
| tonsil | germinal center cells | Medium | Approved |
| tonsil | non-germinal center cells | Low | Approved |
| tonsil | squamous epithelial cells | Low | Approved |
| urinary bladder | urothelial cells | High | Approved |
| Disease name | MONDO ID
|
ICD10
|
ICD10 chapter
|
OMIM
|
Orphanet
|
|---|