Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
1.8.4.12
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor;
peptide-methionine (R)-S-oxide reductase
1.8.4.14
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor;
L-methionine (R)-S-oxide reductase
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 6QA0 | 1.709 | MSRB3 - AA 1-137 |
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0030091 | protein repair |
| Biological Process | GO:0006979 | response to oxidative stress |
| Molecular Function | GO:0033745 | L-methionine-(R)-S-oxide reductase activity |
| Molecular Function | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005739 | mitochondrion |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-5676934 | Protein repair | Leaf | R-HSA-392499 | Metabolism of proteins |
| HPO ID
|
HPO name |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000365 | Hearing impairment |
| HP:0000510 | Rod-cone dystrophy |
| HP:0003577 | Congenital onset |
| Disease name | MONDO ID
|
ICD10
|
ICD10 chapter
|
OMIM
|
Orphanet
|
|---|---|---|---|---|---|
| autosomal recessive nonsyndromic hearing loss 74 | MONDO:0013386 | H90 | chapter8, Diseases of the ear and mastoid process | OMIM:613718 |