Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
1.8.4.12
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor;
peptide-methionine (R)-S-oxide reductase
1.8.4.14
Oxidoreductases;
Acting on a sulfur group of donors;
With a disulfide as acceptor;
L-methionine (R)-S-oxide reductase
PDB | Resolution (Å) | PDB name |
---|---|---|
6QA0 | 1.709 | MSRB3 - AA 1-137 |
GO ontology | GO term | GO description |
---|---|---|
Biological Process | GO:0030091 | protein repair |
Biological Process | GO:0006979 | response to oxidative stress |
Molecular Function | GO:0033745 | L-methionine-(R)-S-oxide reductase activity |
Molecular Function | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity |
Molecular Function | GO:0008270 | zinc ion binding |
Cellular Component | GO:0005737 | cytoplasm |
Cellular Component | GO:0005829 | cytosol |
Cellular Component | GO:0005783 | endoplasmic reticulum |
Cellular Component | GO:0005739 | mitochondrion |
Reactome | Reactome Name | Node type | Reactome Root | Reactome Root Name |
---|---|---|---|---|
R-HSA-5676934 | Protein repair | Leaf | R-HSA-392499 | Metabolism of proteins |
HPO ID | HPO name |
---|---|
HP:0000007 | Autosomal recessive inheritance |
HP:0000365 | Hearing impairment |
HP:0000510 | Rod-cone dystrophy |
HP:0003577 | Congenital onset |
Disease name | MONDO ID | ICD10 | ICD10 chapter | OMIM | Orphanet |
---|---|---|---|---|---|
autosomal recessive nonsyndromic hearing loss 74 | MONDO:0013386 | H90 | chapter8, Diseases of the ear and mastoid process | OMIM:613718 |