Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
1.1.1.12
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor;
L-arabinitol 4-dehydrogenase
1.1.1.239
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor;
3α(17β)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.62
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor;
17β-estradiol 17-dehydrogenase
| GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0008209 | androgen metabolic process |
| Biological Process | GO:0006703 | estrogen biosynthetic process |
| Biological Process | GO:0006633 | fatty acid biosynthetic process |
| Biological Process | GO:0051290 | protein heterotetramerization |
| Molecular Function | GO:0106386 | (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity |
| Molecular Function | GO:0044594 | 17-beta-hydroxysteroid dehydrogenase (NAD+) activity |
| Molecular Function | GO:0070404 | NADH binding |
| Molecular Function | GO:0004303 | estradiol 17-beta-dehydrogenase NAD(P) activity |
| Molecular Function | GO:0047035 | testosterone dehydrogenase (NAD+) activity |
| Cellular Component | GO:0005740 | mitochondrial envelope |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:1990204 | oxidoreductase complex |
| Cellular Component | GO:0005886 | plasma membrane |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-75105 | Fatty acyl-CoA biosynthesis | Internal node | R-HSA-1430728 | Metabolism |
| Location
|
ECO term
|
Pubmed |
|---|---|---|
| Mitochondrion matrix | ECO:0000269 | PubMed:19571038 |