Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
1.1.1.12
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor;
L-arabinitol 4-dehydrogenase
1.1.1.239
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor;
3α(17β)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.62
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor;
17β-estradiol 17-dehydrogenase
GO ontology | GO term | GO description |
---|---|---|
Biological Process | GO:0008209 | androgen metabolic process |
Biological Process | GO:0006703 | estrogen biosynthetic process |
Biological Process | GO:0006633 | fatty acid biosynthetic process |
Biological Process | GO:0051290 | protein heterotetramerization |
Molecular Function | GO:0106386 | (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity |
Molecular Function | GO:0044594 | 17-beta-hydroxysteroid dehydrogenase (NAD+) activity |
Molecular Function | GO:0070404 | NADH binding |
Molecular Function | GO:0004303 | estradiol 17-beta-dehydrogenase NAD(P) activity |
Molecular Function | GO:0047035 | testosterone dehydrogenase (NAD+) activity |
Cellular Component | GO:0005740 | mitochondrial envelope |
Cellular Component | GO:0005759 | mitochondrial matrix |
Cellular Component | GO:1990204 | oxidoreductase complex |
Cellular Component | GO:0005886 | plasma membrane |
Reactome | Reactome Name | Node type | Reactome Root | Reactome Root Name |
---|---|---|---|---|
R-HSA-75105 | Fatty acyl-CoA biosynthesis | Internal node | R-HSA-1430728 | Metabolism |
Location | ECO term | Pubmed |
---|---|---|
Mitochondrion matrix | ECO:0000269 | PubMed:19571038 |