Protein family
Protein sequence
Protein function
Catalytic activity
EC number
EC number description
2.7.7.1
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases;
nicotinamide-nucleotide adenylyltransferase
2.7.7.18
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases;
nicotinate-nucleotide adenylyltransferase
PDB | Resolution (Å) | PDB name |
---|---|---|
1NUP | 1.9 | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE COMPLEX WITH NMN |
1NUQ | 1.9 | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE COMPLEXED WITH NaAD |
1NUR | 2.15 | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE |
1NUS | 2.2 | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE COMPLEXED WITH ATP ANALOG AND NMN |
1NUT | 1.9 | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE COMPLEXED WITH ATP ANALOG |
1NUU | 1.9 | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE COMPLEXED WITH NAD |
GO ontology | GO term | GO description |
---|---|---|
Biological Process | GO:0009435 | NAD biosynthetic process |
Biological Process | GO:0009165 | nucleotide biosynthetic process |
Molecular Function | GO:0005524 | ATP binding |
Molecular Function | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity |
Molecular Function | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity |
Cellular Component | GO:0005759 | mitochondrial matrix |
Cellular Component | GO:0005739 | mitochondrion |
InterPro | InterPro name |
---|---|
IPR004821 | Cytidyltransferase-like domain |
IPR005248 | Nicotinate/nicotinamide nucleotide adenylyltransferase |
IPR014729 | Rossmann-like alpha/beta/alpha sandwich fold |
IPR045094 | Nicotinamide/nicotinate mononucleotide adenylyltransferase, eukaryotic |
Pfam | Pfam name |
---|---|
PF01467 | Cytidylyltransferase-like |
Reactome | Reactome Name | Node type | Reactome Root | Reactome Root Name |
---|---|---|---|---|
R-HSA-196807 | Nicotinate metabolism | Internal node | R-HSA-1430728 | Metabolism |
Location | ECO term | Pubmed |
---|---|---|
Mitochondrion | ECO:0000269 | PubMed:12574164 |
Mitochondrion | ECO:0000269 | PubMed:16118205 |