Structure
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 3LFM | 2.5 | Crystal structure of the fat mass and obesity associated (FTO) protein reveals basis for its substrate specificity |
| 4CXW | 3.1 | Crystal structure of human FTO in complex with subfamily-selective inhibitor 12 |
| 4CXX | 2.76 | Crystal structure of human FTO in complex with acylhydrazine inhibitor 16 |
| 4CXY | 2.65 | Crystal structure of human FTO in complex with acylhydrazine inhibitor 21 |
| 4IDZ | 2.46 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-oxalylglycine (NOG) |
| 4IE0 | 2.53 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with pyridine-2,4-dicarboxylate (2,4-PDCA) |
| 4IE4 | 2.5048 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with 5-carboxy-8-hydroxyquinoline (IOX1) |
| 4IE5 | 1.95 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-[(3-hydroxypyridin-2-yl)carbonyl]glycine (MD6) |
| 4IE6 | 2.5036 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) |
| 4IE7 | 2.6004 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with citrate and rhein (RHN) |
| 4QHO | 2.37 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with CCO10 |
| 4QKN | 2.2 | Crystal structure of FTO bound to a selective inhibitor |
| 4ZS2 | 2.16 | Structural complex of FTO/fluorescein |
| 4ZS3 | 2.45 | Structural complex of 5-aminofluorescein bound to the FTO protein |
| 5DAB | 2.1 | Crystal structure of FTO-IN115 |
| 5F8P | 2.2 | A Novel Inhibitor of the Obesity-Related Protein FTO |
| 5ZMD | 3.3 | Crystal structure of FTO in complex with m6dA modified ssDNA |
| 6AEJ | 2.8 | Crystal structure of human FTO in complex with small-molecule inhibitors |
| 6AK4 | 2.8 | Crystal structure of human FTO in complex with small-molecule inhibitors |
| 6AKW | 2.2 | Crystal structure of RNA dioxygenase bound with an inhibitor |
| 7CKK | 2.35 | Structural complex of FTO bound with Dac51 |
| 7E8Z | 2.55 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with SS81 |
| 7WCV | 2.3 | Co-crystal structure of FTO bound to 6e |
