| 4HLK |
2.0 |
Crystal structure of Tankyrase 2 in complex with 4'-methylflavone |
| 4L32 |
1.85 |
Tankyrase 2 in complex with 2-[4-(4-methylpiperazine-1-carbonyl)phenyl]chromen-4-one |
| 4BUS |
1.9 |
Crystal structure of human tankyrase 2 in complex with 2-(4-(4-oxo-3, 4-dihydroquinazolin-2-yl)phenoxy)acetic acid |
| 4UI3 |
2.0 |
Crystal structure of human tankyrase 2 in complex with TA-26 |
| 3P0P |
2.49 |
Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor |
| 4HKI |
2.15 |
Tankyrase 2 in complex with flavone |
| 5JRT |
1.53 |
Crystal structure of the human Tankyrase 2 (TNKS2) SAM domain (DH902/924RE) |
| 4HL5 |
2.2 |
Complex structure of human tankyrase 2 with 7-hydroxy -4'-methoxyflavone |
| 4BUI |
1.95 |
Crystal structure of human tankyrase 2 in complex with methyl 4-(4- oxo-3,4-dihydroquinazolin-2-yl)benzoate |
| 4BUW |
1.85 |
Crystal structure of human tankyrase 2 in complex with 2-(4-(2-oxo-1, 3-oxazolidin-3-yl)phenyl)-3,4-dihydroquinazolin-4-one |
| 4UI5 |
1.65 |
Crystal structure of human tankyrase 2 in complex with TA-41 |
| 7O6X |
2.2 |
Tankyrase 2 in complex with an inhibitor (OM-153) |
| 4AVU |
2.4 |
Crystal structure of human tankyrase 2 in complex with 6(5H)- phenanthridinone |
| 8ALY |
2.98 |
Cryo-EM structure of human tankyrase 2 SAM-PARP filament (G1032W mutant) |
| 4L09 |
2.05 |
Crystal structure of human tankyrase 2 in complex with 4-(4-oxo-4H-chromen-2-yl)benzoic acid |
| 4BUE |
1.6 |
Crystal structure of human tankyrase 2 in complex with 3-methyl-N-(4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)butanamide |
| 4BUV |
1.8 |
Crystal structure of human tankyrase 2 in complex with N-(4-(4-oxo-3, 4-dihydroquinazolin-2-yl)phenyl)thiophene-2-carboxamide |
| 4UFY |
1.7 |
Crystal structure of human tankyrase 2 in complex with TA-13 |
| 4IUE |
2.38 |
Tankyrase in complex with 7-(2-fluorophenyl)-4-methyl-1,2-dihydroquinolin-2-one |
| 5AL4 |
1.9 |
Crystal structure of TNKS2 in complex with 2-(4-methylpiperazin-1-yl)- 3,4,5,6,7,8-hexahydroquinazolin-4-one |
| 5C5P |
1.75 |
CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR |
| 4HMH |
2.3 |
Crystal structure of tankyrase 2 in complex with 7,3-dihydroxyflavone |
| 3TWT |
1.85 |
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 (chimeric peptide) |
| 4J21 |
1.93 |
Tankyrase 2 in complex with 7-(4-amino-2-chlorophenyl)-4-methylquinolin-2(1H)-one |
| 4UI7 |
1.8 |
Crystal structure of human tankyrase 2 in complex with TA-49 |
| 4BUY |
1.9 |
Crystal structure of human tankyrase 2 in complex with 5-methyl-5-(4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl)imidazolidine-2,4-dione |
| 5DCZ |
2.23 |
Tankyrase 2 complexed with a selective inhibitor |
| 4BU3 |
2.15 |
Crystal structure of human tankyrase 2 in complex with 2-phenyl-3,4- dihydroquinazolin-4-one |
| 5ADT |
2.15 |
Crystal structure of human tankyrase 2 in complex with OD73 |
| 4TJY |
1.9 |
Crystal Structure of human Tankyrase 2 in complex with ABT-888. |
| 4J1Z |
2.0 |
Tankyrase 2 in complex with 4-chloro-1,2-dihydrophatalzin-one |
| 4PML |
1.87 |
Crystal Structure of human Tankyrase 2 in complex with 3-amino-benzamide. |
| 4BUA |
1.85 |
Crystal structure of human tankyrase 2 in complex with 2-(4-(methylsulfanyl)phenyl)-3,4-dihydroquinazolin-4-one |
| 3TWU |
1.8 |
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1 |
| 5C5Q |
2.0 |
CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR |
| 4UHG |
1.7 |
Crystal structure of human tankyrase 2 in complex with TA-21 |
| 3TWS |
1.7 |
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human TERF1 (chimeric peptide) |
| 3P0Q |
1.9 |
Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor |
| 3TWW |
2.0 |
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human LNPEP (chimeric peptide) |
| 4L2K |
2.1 |
Tankyrase 2 in complex with 2-(1,3-benzodioxol-5-yl)-4H-chromen-4-one |
| 6TKM |
2.7 |
Tankyrase 2 in complex with an inhibitor (OM-1800) |
| 4BU9 |
1.65 |
Crystal structure of human tankyrase 2 in complex with 2-(4- methoxyphenyl)-3,4-dihydroquinazolin-4-one |
| 4BJ9 |
2.05 |
Crystal structure of human tankyrase 2 in complex with EB-47 |
| 4UVZ |
1.6 |
Crystal structure of human tankyrase 2 in complex with 5-amino-3- phenyl-1,2-dihydroisoquinolin-1-one |
| 4PNN |
1.65 |
Crystal Structure of human Tankyrase 2 in complex with 4HQN. |
| 4HYF |
2.8 |
Structural basis and SAR for OD 270, a lead stage 1,2,4-triazole based specific Tankyrase1/2 inhibitor |
| 5AEH |
1.85 |
Crystal structure of human tankyrase 2 in complex with OD332 |
| 4BJB |
2.3 |
Crystal structure of human tankyrase 2 in complex with PJ-34 |
| 4M7B |
1.95 |
Human tankyrase 2 - catalytic Parp domain in complex with an inhibitor UPF1854 |
| 4UVU |
1.95 |
Crystal structure of human tankyrase 2 in complex with 1-((4-(5- methyl-1-oxo-1,2-dihydroisoquinolin-3-yl)phenyl)methyl)pyrrolidin-1- ium |
| 3U9H |
1.75 |
Complex structure of human tankyrase 2 with nicotinamide |
| 4W5I |
1.95 |
Crystal structure of human tankyrase 2 in complex with 1-methyl-7-phenyl-1,2,3,4,5,6-hexahydro-1,6- naphthyridin-5-one |
| 4AVW |
2.15 |
Crystal structure of human tankyrase 2 in complex with TIQ-A |
| 5AL3 |
1.75 |
Crystal structure of TNKS2 in complex with 2-(2,4-dichlorophenyl)-1- methyl-1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one |
| 4J3M |
1.9 |
Tankyrase 2 in complex with 3-chloro-4-(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)benzoic acid |
| 5BXU |
1.35 |
Human Tankyrase-2 in Complex with Macrocyclised Extended Peptide cp4n4m5 |
| 5FPG |
2.75 |
Crystal structure of human tankyrase 2 in complex with TA-92 |
| 5C5R |
1.55 |
CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR |
| 5BXO |
1.334 |
Human Tankyrase-2 in Complex with Macrocyclised Extended Peptide cp4n2m3 |
| 5AKU |
1.8 |
Crystal structure of TNKS2 in complex with 2-(4-tert-butylphenyl)-1,2, 3,4-tetrahydroquinazolin-4-one |
| 5OWT |
2.2 |
Crystal structure of TNKS2 in complex with (5S)-5-methyl-5-[4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl]imidazolidine-2,4-dione |
| 4UFU |
2.1 |
Crystal structure of human tankyrase 2 in complex with TA-12 |
| 4TK0 |
1.65 |
Crystal Structure of human Tankyrase 2 in complex with DPQ. |
| 7POX |
2.5 |
TNKS2 in complex with OM-1700, treated with H2O2 |
| 4UVW |
2.1 |
Crystal structure of human tankyrase 2 in complex with 4,5-dimethyl-3- phenyl-1,2-dihydroisoquinolin-1-one |
| 4UX4 |
1.8 |
Crystal structure of human tankyrase 2 in complex with 1-methyl-7-(4- methylphenyl)-5-oxo-5,6-dihydro-1,6-naphthyridin-1-ium |
| 4UVN |
2.2 |
Crystal structure of human tankyrase 2 in complex with 5-amino-3-(4- chlorophenyl)-1,2-dihydroisoquinolin-1-one |
| 4UVT |
1.95 |
Crystal structure of human tankyrase 2 in complex with 5-amino-4- methyl-1,2-dihydroisoquinolin-1-one |
| 4HLM |
1.95 |
Crystal structure of Tankyrase 2 in complex with 3',4'-Dihydroxyflavone |
| 5AL2 |
1.9 |
Crystal structure of TNKS2 in complex with 2-(4-(propan-2-yl)phenyl)- 1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one |
| 4BUF |
2.5 |
Crystal structure of human tankyrase 2 in complex with 2-(4- acetylphenyl)-3,4-dihydroquinazolin-4-one |
| 4UI8 |
2.05 |
Crystal structure of human tankyrase 2 in complex with TA-55 |
| 4J3L |
2.09 |
Tankyrase 2 in complex with 3-chloro-N-(2-methoxyethyl)-4-(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)benzamide |
| 4HKN |
2.05 |
Complex structure of human tankyrase 2 with luteolin |
| 4TJU |
1.57 |
Crystal Structure of human Tankyrase 2 in complex with 3,4-CPQ-5-C. |
| 4HLG |
2.0 |
Crystal structure of Tankyrase 2 in complex with 3'-hydroxyflavone |
| 4BUX |
1.95 |
Crystal structure of human tankyrase 2 in complex with 3-((4-(4-oxo-3, 4-dihydroquinazolin-2-yl)phenyl)methyl)imidazolidine-2,4-dione |
| 6TKR |
2.75 |
Tankyrase 2 in complex with an inhibitor (OM-1704) |
| 4HLH |
1.75 |
Crystal structure of Tankyrase 2 in complex with 4'-fluoroflavone |
| 5AL5 |
2.05 |
Crystal structure of TNKS2 in complex with 2-(4-((pyridin-4-yl)methyl) piperazin-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one |
| 4J22 |
2.12 |
Tankyrase 2 in complex with 3-chloro-4-(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide |
| 4BUT |
1.9 |
Crystal structure of human tankyrase 2 in complex with 4-(4-oxo-3,4- dihydroquinazolin-2-yl)benzene-1-sulfonamide |
| 5NUT |
1.6 |
Crystal structure of TNKS2 in complex with 2-[4-(propan-2-yloxy)phenyl]-3,4-dihydroquinazolin-4-one |
| 4L2F |
2.05 |
Tankyrase 2 in complex with 6-chloro flavone |
| 4BJC |
2.2 |
Crystal structure of human tankyrase 2 in complex with Rucaparib |
| 4UVV |
1.9 |
Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methyl-1,2-dihydroisoquinolin-1-one |
| 4KZQ |
2.25 |
Crystal structure of human tankyrase 2 in complex with 4' -hydroxy flavone |
| 3MHJ |
1.8 |
Human tankyrase 2 - catalytic PARP domain in complex with 1-methyl-3-(trifluoromethyl)-5h-benzo[c][1,8]naphtyridine-6-one |
| 4BUU |
1.6 |
Crystal structure of human tankyrase 2 in complex with (4-(4-oxo-3,4- dihydroquinazolin-2-yl)phenyl)methanesulfonamide |
| 4UI6 |
1.8 |
Crystal structure of human tankyrase 2 in complex with TA-47 |
| 6TKN |
2.5 |
Tankyrase 2 in complex with an inhibitor (OM-1000) |
| 4PNL |
1.5 |
Crystal structure of TNKS-2 in complex with DR2313. |
| 4KZU |
2.1 |
Crystal structure of human tankyrase 2 in complex with 4' -bromo flavone |
| 6TKQ |
2.5 |
Tankyrase 2 in complex with an inhibitor (OM-2700) |
| 3W51 |
2.0 |
Tankyrase in complex with 2-hydroxy-4-methylquinoline |
| 3UA9 |
2.15 |
Crystal structure of human tankyrase 2 in complex with a selective inhibitor |
| 4L0B |
1.8 |
Tankyrase 2 in complex with 4'-dimethylamino flavone |
| 3KR8 |
2.1 |
Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939 |
| 4Z68 |
1.859 |
Hybrid structural analysis of the Arp2/3 regulator Arpin identifies its acidic tail as a primary binding epitope |
| 4BU5 |
1.8 |
Crystal structure of human tankyrase 2 in complex with 2-(4- hydroxyphenyl)-3,4-dihydroquinazolin-4-one |
| 4UVX |
1.95 |
Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-fluoro-1,2-dihydroisoquinolin-1-one |
| 5NOB |
1.85 |
Crystal structure of human tankyrase 2 in complex with OD336 |
| 5NSP |
2.3 |
Crystal structure of TNKS2 in complex with OD334 |
| 4BU8 |
1.85 |
Crystal structure of human tankyrase 2 in complex with 4-(4-oxo-1,4- dihydroquinazolin-2-yl)benzonitrile |
| 3TWV |
2.301 |
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human NUMA1 (chimeric peptide) |
| 4L31 |
2.0 |
Tankyrase 2 in complex with methyl 4-(4-oxochromen-2-yl)benzoate |
| 3TWX |
1.8 |
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide) |
| 5ADQ |
2.1 |
Crystal structure of human tankyrase 2 in complex with JW55 |
| 4UI4 |
2.4 |
Crystal structure of human tankyrase 2 in complex with TA-29 |
| 4BS4 |
1.89 |
Crystal structure of human tankyrase 2 in complex with 4'-isopropylflavone |
| 4L34 |
1.8 |
Tankyrase 2 in complex with 4'-tetrazole flavone |
| 4PNT |
1.6 |
Crystal Structure of human Tankyrase 2 in complex with 1,5-IQD. |
| 4UVY |
1.95 |
Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methoxy-1,2- dihydroisoquinolin-1-one |
| 4L0T |
2.1 |
Tankyrase 2 in complex with 4'-nitro flavone |
| 3U9Y |
2.3 |
Crystal structure of human tankyrase 2 catalytic domain in complex with olaparib |
| 5OWS |
1.8 |
Crystal structure of TNKS2 in complex with 2-[4-(4-methyl-2-oxoimidazolidin-4-yl)phenyl]-3,4-dihydroquinazolin-4-one |
| 5AKW |
2.07 |
Crystal structure of TNKS2 in complex with 2-(4-chlorophenyl)-1,2,3,4- tetrahydroquinazolin-4-one |
| 4UVL |
2.0 |
Crystal structure of human tankyrase 2 in complex with 5-amino-1,2- dihydroisoquinolin-1-one |
| 4BFP |
2.4 |
Crystal structure of human tankyrase 2 in complex with WIKI4 |
| 4PNS |
1.65 |
Crystal Structure of human Tankyrase 2 in complex with INH2BP. |
| 3TWR |
1.55 |
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human 3BP2 |
| 5ADS |
1.8 |
Crystal structure of human tankyrase 2 in complex with OD39 |
| 4BU7 |
2.05 |
Crystal structure of human tankyrase 2 in complex with 2-(4- bromophenyl)-3,4-dihydroquinazolin-4-one |
| 3MHK |
2.3 |
Human tankyrase 2 - catalytic PARP domain in complex with 2-(2-pyridyl)-7,8-dihydro-5h-thiino[4,3-d]pyrimidin-4-ol |
| 2Y0I |
2.28 |
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER) |
| 4TK5 |
2.02 |
Crystal Structure of human Tankyrase 2 in complex with EB47. |
| 4KZL |
2.0 |
Crystal structure of human tankyrase 2 in complex with 4'-fluoro flavone |
| 4HLF |
2.15 |
Crystal structure of Tankyrase 2 in complex with 7,3',4'-Trihydroxyflavone |
| 7R3Z |
2.25 |
Tankyrase 2 catalytic domain in complex with OUL40 |
| 3P0N |
1.9 |
Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor |
| 3TWQ |
2.151 |
Crystal structure of ARC4 from human Tankyrase 2 (apo form) |
| 4TKG |
1.95 |
Crystal Structure of human Tankyrase 2 in complex with AZD2281. |
| 4PNR |
1.71 |
Crystal Structure of human Tankyrase 2 in complex with TIQ-A. |
| 4BU6 |
1.8 |
Crystal structure of human tankyrase 2 in complex with 2-(4- aminophenyl)-3,4-dihydroquinazolin-4-one |
| 4TJW |
1.7 |
Crystal Structure of human Tankyrase 2 in complex with PJ-34. |
| 4L2G |
2.05 |
Tankyrase 2 in complex with 6- fluoro flavone |
| 5ADR |
2.1 |
Crystal structure of human tankyrase 2 in complex with OD38 |
| 4TKF |
2.6 |
Crystal Structure of human Tankyrase 2 in complex with IWR-1. |
| 4PNQ |
1.85 |
Crystal Structure of human Tankyrase 2 in complex with 5AIQ. |
| 4L0I |
2.3 |
Tankyrase 2 catalytic domain in complex with ethyl 4-(4-oxo-4H-chromen-2-yl)benzoate |
| 6TKP |
2.4 |
Tankyrase 2 in complex with an inhibitor (OM-1900) |
| 6TG4 |
2.76 |
Tankyrase 2 in complex with an inhibitor (OM-1700) |
| 4UVS |
2.0 |
Crystal structure of human tankyrase 2 in complex with 5-amino-3- pentyl-1,2-dihydroisoquinolin-1-one |
| 7A1S |
2.01 |
FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH ZN(II), 3-methyl-2-oxoglutarate, AND TANKYRASE-2 (TNKS2) FRAGMENT PEPTIDE (21-MER) |
| 4BUD |
2.5 |
Crystal structure of human tankyrase 2 in complex with 2-(4-tert- butylphenyl)-1,4-dihydroquinazolin-4-one |
| 3KR7 |
1.95 |
Human tankyrase 2 - catalytic PARP domain |
| 5AL1 |
1.75 |
Crystal structure of TNKS2 in complex with 2-(4-tert-butylphenyl)-1H, 2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one |
| 4UVP |
1.75 |
Crystal structure of human tankyrase 2 in complex with 5-amino-3- ethyl-1,2-dihydroisoquinolin-1-one |
| 4PNM |
2.19 |
Crystal Structure of human Tankyrase 2 in complex with Nu1025. |
| 4L0V |
1.7 |
Tankyrase 2 in complex with 4'-chloro flavone |
| 4UVO |
1.85 |
Crystal structure of human tankyrase 2 in complex with 5-amino-3-(4- methoxyphenyl)-1,2-dihydroisoquinolin-1-one |
| 4L33 |
2.1 |
Tankyrase 2 in complex with cyanomethyl 4-(4-oxo-4H-chromen-2-yl)benzoate |
| 6TKS |
2.5 |
Tankyrase 2 in complex with an inhibitor (OM-1720) |
| 4L0S |
1.9 |
Tankyrase 2 in complex with 4'-cyano flavone |
| 4TKI |
2.15 |
Crystal Structure of human Tankyrase 2 in complex with BSI-201. |
| 5FPF |
2.6 |
Crystal structure of human tankyrase 2 in complex with TA-91 |
| 4L10 |
1.7 |
Tankyrase 2 in complex with 4'-methoxy flavone |
| 4HKK |
1.95 |
Complex structure of human tankyrase 2 with apigenin |
