Structure
| PDB | Resolution (Å) | PDB name |
|---|---|---|
| 2N16 | Solution structure of G-quadruplex recognition domain of RHAU | |
| 2N21 | Solution structure of complex between DNA G-quadruplex and G-quadruplex recognition domain of RHAU | |
| 6Q6R | 1.5 | Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex |
Showing 1 to 3 of 3 entries
GO term
GO ontology
| GO term | GO description |
|---|---|---|
| Biological Process | GO:0061158 | 3'-UTR-mediated mRNA destabilization |
| Biological Process | GO:0044806 | G-quadruplex DNA unwinding |
| Biological Process | GO:0010501 | RNA secondary structure unwinding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0034644 | cellular response to UV |
| Biological Process | GO:1903843 | cellular response to arsenite ion |
| Biological Process | GO:0034605 | cellular response to heat |
| Biological Process | GO:0051607 | defense response to virus |
| Biological Process | GO:0045087 | innate immune response |
| Biological Process | GO:0017148 | negative regulation of translation |
Showing 1 to 10 of 63 entries
InterPro / Pfam
| InterPro
| InterPro name |
|---|---|
| IPR001650 | Helicase, C-terminal |
| IPR002464 | DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site |
| IPR007502 | Helicase-associated domain |
| IPR011545 | DEAD/DEAH box helicase domain |
| IPR011709 | DEAD-box helicase, OB fold |
| IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Showing 1 to 7 of 7 entries
Reactome
| Reactome
| Reactome Name | Node type
| Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-3134963 | DEx/H-box helicases activate type I IFN and inflammatory cytokines production | Leaf | R-HSA-168256 | Immune System |
Showing 1 to 1 of 1 entries
Subcellular location
| Location
| ECO term
| Pubmed |
|---|---|---|
| Cell projection, axon | ECO:0000250 | |
| Cell projection, dendrite | ECO:0000250 | |
| Chromosome, telomere | ECO:0000269 | PubMed:20472641 |
| Cytoplasm | ECO:0000269 | PubMed:14731398 |
| Cytoplasm | ECO:0000269 | PubMed:18279852 |
| Cytoplasm | ECO:0000269 | PubMed:18854321 |
| Cytoplasm, cytosol | ECO:0000250 | |
| Cytoplasm, Stress granule | ECO:0000269 | PubMed:18854321 |
| Mitochondrion | ECO:0000250 | |
| Nucleus | ECO:0000269 | PubMed:14731398 |
Showing 1 to 10 of 14 entries
Interactor | Variant | Drug
Tissue and cell type
| Tissue
| Cell type
| Expression level | Reliability |
|---|---|---|---|
| adipose tissue | adipocytes | Low | Approved |
| adrenal gland | glandular cells | High | Approved |
| appendix | glandular cells | High | Approved |
| appendix | lymphoid tissue | Medium | Approved |
| bone marrow | hematopoietic cells | Medium | Approved |
| breast | glandular cells | High | Approved |
| breast | myoepithelial cells | High | Approved |
| bronchus | respiratory epithelial cells | Medium | Approved |
| caudate | glial cells | Low | Approved |
| caudate | neuronal cells | High | Approved |
Showing 1 to 10 of 79 entries