Protein family
The protein has not catalytic activity
Protein sequence
Protein function
Publications
Catalytic activity
| PDB | Resolution (Å) | PDB name |
|---|
GO ontology
|
GO term | GO description |
|---|---|---|
| Biological Process | GO:0098609 | cell-cell adhesion |
| Biological Process | GO:0007043 | cell-cell junction assembly |
| Biological Process | GO:0002159 | desmosome assembly |
| Biological Process | GO:1902373 | negative regulation of mRNA catabolic process |
| Biological Process | GO:0010628 | positive regulation of gene expression |
| Biological Process | GO:0072659 | protein localization to plasma membrane |
| Molecular Function | GO:0045294 | alpha-catenin binding |
| Molecular Function | GO:0045296 | cadherin binding |
| Molecular Function | GO:0098641 | cadherin binding involved in cell-cell adhesion |
| Molecular Function | GO:0050839 | cell adhesion molecule binding |
| Molecular Function | GO:0019899 | enzyme binding |
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0030054 | cell junction |
| Cellular Component | GO:0005911 | cell-cell junction |
| Cellular Component | GO:0001533 | cornified envelope |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0030057 | desmosome |
| Cellular Component | GO:1990124 | messenger ribonucleoprotein complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005886 | plasma membrane |
| Reactome
|
Reactome Name | Node type
|
Reactome Root | Reactome Root Name |
|---|---|---|---|---|
| R-HSA-6805567 | Keratinization | Internal node | R-HSA-1266738 | Developmental Biology |
| R-HSA-6809371 | Formation of the cornified envelope | Leaf | R-HSA-1266738 | Developmental Biology |
| HPO ID
|
HPO name |
|---|
| Tissue
|
Cell type
|
Expression level | Reliability |
|---|---|---|---|
| adipose tissue | adipocytes | Low | Enhanced |
| adrenal gland | glandular cells | Low | Enhanced |
| appendix | glandular cells | Low | Enhanced |
| bone marrow | hematopoietic cells | Low | Enhanced |
| breast | adipocytes | Low | Enhanced |
| bronchus | respiratory epithelial cells | Low | Enhanced |
| caudate | glial cells | Low | Enhanced |
| caudate | neuronal cells | Low | Enhanced |
| cerebellum | cells in granular layer | Low | Enhanced |
| cerebral cortex | endothelial cells | High | Enhanced |
| cerebral cortex | glial cells | Low | Enhanced |
| cerebral cortex | neuronal cells | Low | Enhanced |
| cerebral cortex | neuropil | Low | Enhanced |
| cervix | squamous epithelial cells | Medium | Enhanced |
| duodenum | glandular cells | Low | Enhanced |
| endometrium 1 | glandular cells | Low | Enhanced |
| esophagus | squamous epithelial cells | High | Enhanced |
| gallbladder | glandular cells | Low | Enhanced |
| heart muscle | cardiomyocytes | Low | Enhanced |
| hippocampus | neuronal cells | Low | Enhanced |
| kidney | cells in tubules | Low | Enhanced |
| lung | alveolar cells type II | Low | Enhanced |
| nasopharynx | respiratory epithelial cells | Low | Enhanced |
| oral mucosa | squamous epithelial cells | High | Enhanced |
| pancreas | exocrine glandular cells | Low | Enhanced |
| parathyroid gland | glandular cells | Low | Enhanced |
| placenta | cytotrophoblasts | High | Enhanced |
| placenta | syncytiotrophoblasts - cell body | High | Enhanced |
| placenta | syncytiotrophoblasts - microvilli | Medium | Enhanced |
| salivary gland | glandular cells | Low | Enhanced |
| skeletal muscle | myocytes | Low | Enhanced |
| skin 1 | cells in basal layer | Medium | Enhanced |
| skin 1 | cells in granular layer | Medium | Enhanced |
| skin 1 | cells in spinous layer | Medium | Enhanced |
| skin 1 | langerhans cells | Medium | Enhanced |
| skin 2 | cells in basal layer | High | Enhanced |
| skin 2 | cells in granular layer | Medium | Enhanced |
| skin 2 | cells in spinous layer | Medium | Enhanced |
| skin 2 | langerhans cells | Medium | Enhanced |
| smooth muscle | smooth muscle cells | Low | Enhanced |
| soft tissue 2 | fibroblasts | Low | Enhanced |
| soft tissue 2 | peripheral nerve | Low | Enhanced |
| testis | Leydig cells | Medium | Enhanced |
| testis | cells in seminiferous ducts | Low | Enhanced |
| thyroid gland | glandular cells | Low | Enhanced |
| tonsil | squamous epithelial cells | Medium | Enhanced |
| urinary bladder | urothelial cells | Medium | Enhanced |
| vagina | squamous epithelial cells | Medium | Enhanced |
| Disease name | MONDO ID
|
ICD10
|
ICD10 chapter
|
OMIM
|
Orphanet
|
|---|