MultifacetedProtDB - Bologna Biocomputing Group

PDB	Resolution (Å)	PDB name
2DAD		Solution structure of the fifth crystall domain of the non-lens protein, Absent in melanoma 1
3CW3	1.88	Crystal structure of AIM1g1
6VRO	2.45	The structure of the PP2A B56 subunit AIM1 complex

GO ontology	GO term	GO description
Molecular Function	GO:0030246	carbohydrate binding

InterPro	InterPro name
IPR000772	Ricin B, lectin domain
IPR001064	Beta/gamma crystallin
IPR011024	Gamma-crystallin-like
IPR035992	Ricin B-like lectins

Pfam	Pfam name
PF00030	Beta/Gamma crystallin
PF00652	Ricin-type beta-trefoil lectin domain

Phenotype

Tissue and cell type

Tissue	Cell type	Expression level	Reliability
adrenal gland	glandular cells	Medium	Approved
appendix	glandular cells	High	Approved
appendix	lymphoid tissue	Low	Approved
bone marrow	hematopoietic cells	Medium	Approved
breast	glandular cells	High	Approved
breast	myoepithelial cells	Low	Approved
bronchus	respiratory epithelial cells	High	Approved
caudate	glial cells	Low	Approved
caudate	neuronal cells	Low	Approved
cerebellum	Purkinje cells	Medium	Approved
cerebral cortex	endothelial cells	Low	Approved
cerebral cortex	glial cells	Low	Approved
cerebral cortex	neuronal cells	Medium	Approved
cerebral cortex	neuropil	Low	Approved
cervix	glandular cells	Medium	Approved
cervix	squamous epithelial cells	Medium	Approved
colon	endothelial cells	Low	Approved
colon	glandular cells	High	Approved
colon	peripheral nerve/ganglion	Medium	Approved
duodenum	glandular cells	High	Approved
endometrium 1	cells in endometrial stroma	Low	Approved
endometrium 1	glandular cells	High	Approved
endometrium 2	glandular cells	Medium	Approved
epididymis	glandular cells	Medium	Approved
esophagus	squamous epithelial cells	High	Approved
fallopian tube	glandular cells	Medium	Approved
gallbladder	glandular cells	High	Approved
heart muscle	cardiomyocytes	Medium	Approved
hippocampus	neuronal cells	Low	Approved
kidney	cells in glomeruli	Low	Approved
kidney	cells in tubules	High	Approved
liver	cholangiocytes	Medium	Approved
liver	hepatocytes	Medium	Approved
lung	macrophages	High	Approved
lymph node	germinal center cells	Medium	Approved
lymph node	non-germinal center cells	Medium	Approved
nasopharynx	respiratory epithelial cells	High	Approved
oral mucosa	squamous epithelial cells	Medium	Approved
ovary	follicle cells	Low	Approved
pancreas	exocrine glandular cells	High	Approved
pancreas	pancreatic endocrine cells	Low	Approved
parathyroid gland	glandular cells	High	Approved
placenta	trophoblastic cells	High	Approved
prostate	glandular cells	High	Approved
rectum	glandular cells	High	Approved
salivary gland	glandular cells	High	Approved
seminal vesicle	glandular cells	Medium	Approved
skeletal muscle	myocytes	Medium	Approved
skin 1	Langerhans	Medium	Approved
skin 1	fibroblasts	Medium	Approved
skin 1	keratinocytes	Medium	Approved
skin 1	melanocytes	Medium	Approved
skin 2	epidermal cells	High	Approved
small intestine	glandular cells	High	Approved
spleen	cells in red pulp	Medium	Approved
spleen	cells in white pulp	Medium	Approved
stomach 1	glandular cells	High	Approved
stomach 2	glandular cells	High	Approved
testis	Leydig cells	Low	Approved
testis	cells in seminiferous ducts	High	Approved
thyroid gland	glandular cells	Medium	Approved
tonsil	germinal center cells	Medium	Approved
tonsil	non-germinal center cells	High	Approved
tonsil	squamous epithelial cells	High	Approved
urinary bladder	urothelial cells	High	Approved
vagina	squamous epithelial cells	Medium	Approved

Summary of Q9Y4K1

Gene: CRYBG1, AIM1
Protein: Beta/gamma crystallin domain-containing protein 1

Structure

GO term

InterPro / Pfam

Reactome

Subcellular location

Interactor | Variant | Drug

Phenotype

Tissue and cell type

Disease

Summary of Q9Y4K1

Gene: CRYBG1, AIM1 Protein: Beta/gamma crystallin domain-containing protein 1

Structure

GO term

InterPro / Pfam

Reactome

Subcellular location

Interactor | Variant | Drug

Phenotype

Tissue and cell type

Disease

Gene: CRYBG1, AIM1
Protein: Beta/gamma crystallin domain-containing protein 1